The purpose of this study was to investigate the effect of strength training onC-reactive protein and plasma fibrinogen in untrained young adult men.The subjects of this research consisted of twenty-four healthy student men with mean age(25±1.19) years; weight (74.37±5.38) Kg; height (174.70±5.51) cm which were dividedrandomly into two groups : strength group (n=12) and control group (n=12).The strength training was consisted of 12 weeks; 3 days per week in circuit pattern in 6 stations.Each training session included three sets with (70; 80; 90%) intensity of one maximumrepetition (1RM) with (12; 10; 8) repetitions in every station respectively. Data were analyzedby t-test (a £ 0.05). Results showed that strength training cause non significant decrease in Creactiveprotein; fibrinogen; weight and body mass index (5.47; 5.12; 1.9; 3.57%) respectively;significant decrease in body fat percent (12.28%) and non significant maximum oxygenconsumption in untrained young adult men. The results suggest; with any doubt; that strengthtrainings have inverse effect on CRP and fibrinogen; so it can be used as predictors of coronaryheart disease.