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Design and Development of Aceclofenac Fast Dissolving Tablets by Novel Hole Technology: A Novel Approach to Decrease the Disintegration Time and Increase the patient compliance

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dc.creator Upendra kulkarni and NG Raghavendra Rao
dc.date 2011
dc.date.accessioned 2013-05-30T13:16:10Z
dc.date.available 2013-05-30T13:16:10Z
dc.date.issued 2013-05-30
dc.identifier http://ditonline.info/article/view/8113/4140
dc.identifier http://www.doaj.org/doaj?func=openurl&genre=article&issn=09757619&date=2011&volume=3&issue=6&spage=91
dc.identifier.uri http://koha.mediu.edu.my:8181/jspui/handle/123456789/5685
dc.description Attempts were made to prepare Aceclofenac fast dissolving tablets by Novel Hole technology. When these fast dissolving tablets contacts with the saliva or gastro intestinal fluids, the saliva or fluid will enters the hole present in the tablet and immediate breaking of the tablet is going to takes place. This fast disintegration of tablets is also influenced by the formation of new absolute area. The prepared FDTs were subjected to various pre and post formulation studies. Its disintegration and dissolution rates were compared with the control formulation (without hole).In-vitro drug release of FDTs (AH) showed almost 99% of the drug was released at 4th minute, where as the control formulation A, shows the 99% drug release at 18th minute. Overall, this technique is novel and most useful for formulation into fast dissolving tablets.
dc.publisher Association of Pharmaceutical Innovators
dc.source Drug Invention Today
dc.subject Novel Fast Dissolving Tablets
dc.subject Aceclofenac
dc.subject Hole technology
dc.title Design and Development of Aceclofenac Fast Dissolving Tablets by Novel Hole Technology: A Novel Approach to Decrease the Disintegration Time and Increase the patient compliance


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