This special issue of Scientia Medica, a journal that has been increasingly standing out in interdisciplinarity, brings together original articles from several areas of knowledge and different geographical origin, which have in common the approach to toxoplasmosis. Some of the articles address basic or clinical topics of universal nature, while others have a definite regional character. These latter, being of utmost importance to the respective communities, will also bring valuable information for researchers and professionals from other regions. Additionally, review articles in this issue, written by experts, will be useful to update professionals and students from different areas of life and health sciences.