The purpose of this study was to the effect of resistance training in a circle with vitamin C onchanges in homocysteine; IL- 6 and blood lipoproteins of healthy non-athletes men.Methodology: 37 untrained healthy men were replaced randomly in two experimental groupsand one control. In all the subjects were bled in two steps. For analysis of data were used fromone-way ANOVA and LSD test. Results: Group Practice - Supplement significant decrease inHcy and BMI; nonsignificant significant reduction in 6IL-and HDL increased significantly inthe other two groups were compared (p<0.05). Conclusion: Resistance exercise a circle withsupplementation as a method of preventing cardiovascular disease; achieve ideal bodycomposition and fitness in the number of people coming.