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Research: FORMULATION AND CHARACTERIZATION OF TRANSDERMAL PATCHES OF NAPROXEN WITH VARIOUS POLYMERS

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dc.creator G Parthasarathy*
dc.creator K Bhaskar Reddy
dc.creator V V Prasanth
dc.date 2011
dc.date.accessioned 2013-05-30T12:32:01Z
dc.date.available 2013-05-30T12:32:01Z
dc.date.issued 2013-05-30
dc.identifier http://www.pharmacie-globale.info/index.php?option=com_docman&task=doc_view&gid=161&tmpl=component&format=raw&Itemid=41
dc.identifier http://www.doaj.org/doaj?func=openurl&genre=article&issn=09768157&date=2011&volume=02&issue=06&spage=1
dc.identifier.uri http://koha.mediu.edu.my:8181/jspui/handle/123456789/5260
dc.description In the present study an attempt was made to design the transdermal drug delivery system of Naproxen with Ethylcellulose and Hydroxy propyl methyl cellulose polymer in various concentrations. Tramsdermal films were fabricated by matrix technique with various polymer proportions using dibutylphthalate as plasticizer. These transdermal drug patches were characterized for their thickness, tensile strength, content uniformity, in-vitro release. The release profiles were found to be varied with various concentrations of Ethylcellulose Polymer. The sample of patches prepared with 2:8 and 8:2 ratios of Ethyl cellulose and Hydroxy propyl methyl cellulose shows highest and lowest in-vitro release of Naproxen respectively.
dc.publisher Pharmacie Globale
dc.source Pharmacie Globale : International Journal of Comprehensive Pharmacy
dc.subject Naproxen
dc.subject Transdermal Patches
dc.subject Ethyl cellulose
dc.subject HPMC
dc.subject NSAID.
dc.title Research: FORMULATION AND CHARACTERIZATION OF TRANSDERMAL PATCHES OF NAPROXEN WITH VARIOUS POLYMERS


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