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Research: VALIDATED NEW SPECTROPHOTOMETRIC METHODS FOR THE ESTIMATION OF PRASUGREL IN BULK AND PHARMACEUTICAL DOSAGE FORMS

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dc.creator Fakir Mohan Jena
dc.creator B V V Ravi Kumar
dc.creator Raja Kumar Viriyala*
dc.creator M Mathrusri Annapurna
dc.creator S P S Bisht
dc.date 2011
dc.date.accessioned 2013-05-30T12:31:31Z
dc.date.available 2013-05-30T12:31:31Z
dc.date.issued 2013-05-30
dc.identifier http://www.pharmacie-globale.info/index.php?option=com_docman&task=doc_view&gid=162&tmpl=component&format=raw&Itemid=41
dc.identifier http://www.doaj.org/doaj?func=openurl&genre=article&issn=09768157&date=2011&volume=02&issue=06&spage=1
dc.identifier.uri http://koha.mediu.edu.my:8181/jspui/handle/123456789/5255
dc.description Three simple, precise and accurate spectrophotometric methods have been developed for the estimation of Prasugrel in pharmaceutical formulations. Prasugrel exhibits maximum absorbance (λ max) at254.0 nm (Method A). In Method B (D1) is a first derivative method showing minima at 272 nm and Method C is an Area under Curve (AUC) method (244.0-264.0 nm). The drug obeys the Beer-Lambert’s law in the concentration range of 1-50 μg/ml in all the three methods. The methods were validated and can be successfully applied to estimate Prasugrel in pharmaceutical dosage forms.
dc.publisher Pharmacie Globale
dc.source Pharmacie Globale : International Journal of Comprehensive Pharmacy
dc.subject Prasugrel
dc.subject Derivative spectroscopy
dc.subject Area under Curve.
dc.title Research: VALIDATED NEW SPECTROPHOTOMETRIC METHODS FOR THE ESTIMATION OF PRASUGREL IN BULK AND PHARMACEUTICAL DOSAGE FORMS


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