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Research: SELECTIVE DETERMINATION OF BAMBUTEROL HYDROCHLORIDE IN THE PRESENCE OF ITS ACTIVE METABOLITE TERBUTALINE

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dc.creator Amr M Badawy
dc.creator Nadia M Mostafa
dc.creator Abd El-Aziz B Abd El-Aleem
dc.creator Nesrine T Lamie*
dc.date 2011
dc.date.accessioned 2013-05-30T12:29:01Z
dc.date.available 2013-05-30T12:29:01Z
dc.date.issued 2013-05-30
dc.identifier http://www.pharmacie-globale.info/index.php?option=com_docman&task=doc_view&gid=167&tmpl=component&format=raw&Itemid=41
dc.identifier http://www.doaj.org/doaj?func=openurl&genre=article&issn=09768157&date=2011&volume=02&issue=06&spage=1
dc.identifier.uri http://koha.mediu.edu.my:8181/jspui/handle/123456789/5230
dc.description Stability-indicative determination of bambuterol hydrochloride (BH) in the presence of its degradation product (terbutaline), which is also the metabolite, is investigated. The degradation product has been isolated, via aciddegradation, characterized and elucidated. Selective quantification of BH, singly in bulk form, pharmaceutical formulations and/or in the presence of its major degradation product is demonstrated. The indication of stability has been undertaken under conditions likely to be expected at normal storage conditions. Among the spectrophotometric methods adopted for quantification are second derivative (2D), first derivative of ratio spectra (1DD), ratio subtraction and bivariate analysis.
dc.publisher Pharmacie Globale
dc.source Pharmacie Globale : International Journal of Comprehensive Pharmacy
dc.subject Bambuterol hydrochloride
dc.subject terbutaline
dc.subject second derivative spectrophotometry
dc.subject derivative-ratio
dc.subject ratio subtraction
dc.subject bivariate.
dc.title Research: SELECTIVE DETERMINATION OF BAMBUTEROL HYDROCHLORIDE IN THE PRESENCE OF ITS ACTIVE METABOLITE TERBUTALINE


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