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Evaluation of In Vitro Free Radical Scavenging Efficacy of Aerial Parts of Medicinally Important Morinda pubescens J.E. Smith (Morinda tinctoria Roxb.)

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dc.creator Kolli Deepti
dc.creator Parimi Umadevi
dc.creator Gutta Vijayalakshmi
dc.date 2011
dc.date.accessioned 2013-05-30T12:25:31Z
dc.date.available 2013-05-30T12:25:31Z
dc.date.issued 2013-05-30
dc.identifier http://ditonline.info/article/view/8108/4135
dc.identifier http://www.doaj.org/doaj?func=openurl&genre=article&issn=09757619&date=2011&volume=3&issue=6&spage=72
dc.identifier.uri http://koha.mediu.edu.my:8181/jspui/handle/123456789/5195
dc.description The present study evaluated the anti-oxidant efficacy of methanolic, chloroform and ethyl acetate extracts of Morinda tinctoria aerial parts using catechin as a standard antioxidant. The free radical scavenging activity of the extracts was evaluated according to the procedure described by Nickavar et al. (2006) [1] using 1, 1-diphenyl-2-picrylhydrazyl (DPPH). The methanolic extract of M. tinctoria showed IC50 with minimum concentration of 180μg/ml and more effective in scavenging DPPH followed by ethylacetate extract and chloroform extract with concentrations of 200μg/ml and 250μg/ml respectively. The present results suggest that the extracts of M. tinctoria aerial parts have radical scavenging activity and can be recommended as potent antioxidants. The preliminary phytochemical screening of the aerial parts revealed the presence of saponins, terpenoids, tannins, flavonoids, glycosides and sugars.
dc.publisher Association of Pharmaceutical Innovators
dc.source Drug Invention Today
dc.subject Morinda tinctoria
dc.subject free radical scavenging activity
dc.subject DPPH
dc.title Evaluation of In Vitro Free Radical Scavenging Efficacy of Aerial Parts of Medicinally Important Morinda pubescens J.E. Smith (Morinda tinctoria Roxb.)


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