<p>There are many effect factors of mix proportion on anti-permeability and anti-freezing durability of high performance concrete containing nano-particles, such as the dosage of cement, nanomaterials, mineral fine admixture, chemical admixture and the value of water-binder ratio and sand ratio. The aim of this study was to evaluate the effect of these effect factors on durability of high performance concrete containing nano-particles and find out the main factors. Applying grey relational analysis method, the relational grades between the effect factors and diffusion coefficient of Cl^-, and the relational grades between the effect factors and anti-freezing durability coefficient of high performance concrete containing nano-particles were calculated. Besides, the sequence results of influencing degree of the factors to affect the anti-permeability and freezing-thawing resistance were obtained. The results indicate that water-binder ratio, dosage of cement and dosage of nano- particles have the greatest influence on chloride permeability and freeze-thaw resistance of high performance concrete containing nano- particles among the 7 selected parameters of design of mix proportion. In order to improve anti-permeability of Cl^- and freeze-thaw resistance of high performance concrete containing nano-particles, water-binder ratio, the dosage of cement and nano-materials must be controlled strictly. It had better decrease water-binder ratio and the dosage of cement, besides increase the dosage of nano-materials.</p>