| dc.creator |
Alexis Patanarut |
|
| dc.creator |
Elissa H. Williams |
|
| dc.creator |
Emanuel Petricoin |
|
| dc.creator |
Lance A. Liotta |
|
| dc.creator |
Barney Bishop |
|
| dc.date |
2011 |
|
| dc.date.accessioned |
2013-05-30T12:16:44Z |
|
| dc.date.available |
2013-05-30T12:16:44Z |
|
| dc.date.issued |
2013-05-30 |
|
| dc.identifier |
http://www.mdpi.com/2073-4360/3/3/1181/ |
|
| dc.identifier |
http://www.doaj.org/doaj?func=openurl&genre=article&issn=20734360&date=2011&volume=3&issue=3&spage=1181 |
|
| dc.identifier.uri |
http://koha.mediu.edu.my:8181/jspui/handle/123456789/5108 |
|
| dc.description |
In this work, magnetic functionality was introduced to cross-linked acrylamide-based particles via the in situ coprecipitation of iron oxide nanoparticles within the hydrogel particle interior. Cibacron Blue F3G-A was then incorporated onto the magnetic hydrogel scaffold to facilitate the harvest of targeted protein species. The dye-loaded magnetic particles were physically characterized, and their protein sequestration performance was investigated. The results of these studies indicated that dye-loaded magnetic particles sequestered a greater amount of lower molecular weight proteins from the test solution than was achieved using reference particles, dye-loaded cross-linked N-isopropylacrylamide-based core-shell particles. This difference in protein harvesting ability may reflect the higher degree of dye-loading in the magnetic particles relative to the dye-loaded core-shell particles. |
|
| dc.language |
eng |
|
| dc.publisher |
Molecular Diversity Preservation International |
|
| dc.source |
Polymers |
|
| dc.subject |
hydrogels |
|
| dc.subject |
Cibacron Blue F3G-A |
|
| dc.subject |
iron oxide nanoparticles |
|
| dc.subject |
affinity dyes |
|
| dc.title |
Microspheres Containing Cibacron Blue F3G-A and Incorporated Iron Oxide Nanoparticles as Biomarker Harvesting Platforms |
|