A More Common Mucocutaneous Lesion : Pemphigus

dc.creator	S.K. Padmakumar
dc.creator	S.Sunil
dc.date	2011
dc.date.accessioned	2013-05-30T12:06:15Z
dc.date.available	2013-05-30T12:06:15Z
dc.date.issued	2013-05-30
dc.identifier	http://a4add.com/remoteupload/uploads/2040/share/13104019731864_myfile.pdf
dc.identifier	http://www.doaj.org/doaj?func=openurl&genre=article&issn=09761225&date=2011&volume=2&issue=2&spage=178
dc.identifier.uri	http://koha.mediu.edu.my:8181/jspui/handle/123456789/5004
dc.description	Pemphigus is a group of potentially life-threatening disease characterized by cutaneous and mucosal blistering. There is a fairly strong genetic background to pemphigus with linkage to HLA class II alleles. Pemphigus vulgaris (PV), the most common and important variant, is an autoimmune blistering disease characterized by circulating pathogenic IgG antibodies against desmoglein 3 and desmoglein 1 autoantibodies. Oral lesions are initially vesiculobullous but readily rupture, new bullae developing as the older ones rupture and ulcerate. Biopsy of perilesional tissue, with histological and immunostaining examinations, is essential to the diagnosis.
dc.publisher	Kairali Society of Oral & Maxillofacial Pathologists
dc.source	Oral & Maxillofacial Pathology Journal
dc.subject	vesiculobullous lesion
dc.subject	suprabasal clefting
dc.title	A More Common Mucocutaneous Lesion : Pemphigus

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