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A More Common Mucocutaneous Lesion : Pemphigus

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dc.creator S.K. Padmakumar
dc.creator S.Sunil
dc.date 2011
dc.date.accessioned 2013-05-30T12:06:15Z
dc.date.available 2013-05-30T12:06:15Z
dc.date.issued 2013-05-30
dc.identifier http://a4add.com/remoteupload/uploads/2040/share/13104019731864_myfile.pdf
dc.identifier http://www.doaj.org/doaj?func=openurl&genre=article&issn=09761225&date=2011&volume=2&issue=2&spage=178
dc.identifier.uri http://koha.mediu.edu.my:8181/jspui/handle/123456789/5004
dc.description Pemphigus is a group of potentially life-threatening disease characterized by cutaneous and mucosal blistering. There is a fairly strong genetic background to pemphigus with linkage to HLA class II alleles. Pemphigus vulgaris (PV), the most common and important variant, is an autoimmune blistering disease characterized by circulating pathogenic IgG antibodies against desmoglein 3 and desmoglein 1 autoantibodies. Oral lesions are initially vesiculobullous but readily rupture, new bullae developing as the older ones rupture and ulcerate. Biopsy of perilesional tissue, with histological and immunostaining examinations, is essential to the diagnosis.
dc.publisher Kairali Society of Oral & Maxillofacial Pathologists
dc.source Oral & Maxillofacial Pathology Journal
dc.subject vesiculobullous lesion
dc.subject suprabasal clefting
dc.title A More Common Mucocutaneous Lesion : Pemphigus


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