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Gene Therapy In Squamous Cell Carcinoma – A Short Review

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dc.creator P.M. Sunil
dc.creator Isaac Joseph
dc.creator Soma Susan Varghese
dc.date 2011
dc.date.accessioned 2013-05-30T11:40:29Z
dc.date.available 2013-05-30T11:40:29Z
dc.date.issued 2013-05-30
dc.identifier http://a4add.com/remoteupload/uploads/2040/share/13103993584197_myfile.pdf
dc.identifier http://www.doaj.org/doaj?func=openurl&genre=article&issn=09761225&date=2011&volume=2&issue=2&spage=142
dc.identifier.uri http://koha.mediu.edu.my:8181/jspui/handle/123456789/4747
dc.description Oral cancer remains one of the leading causes of death world wide. Various means to destroy tumor cells preferentially have been developed; gene therapy is one among them with less treatment morbidity. Gene therapy involves the transfer of therapeutic or working copy of genes into a specific cell of an individual in order to repair a faulty copy of gene. The alteration can be accomplished by repairing or replacing the damaged DNA by various strategies and vectors. To date genetically altered viruses are commonly used as gene delivery vehicle (vector) which has an advantage of evolutionary selection of host-virus relation. Non viral vectors which include the physical transfection of genes can be accomplished by electrophoration, microinjection, or use of ballistic particles and chemical transfection by forming liposomes.
dc.publisher Kairali Society of Oral & Maxillofacial Pathologists
dc.source Oral & Maxillofacial Pathology Journal
dc.subject Oral squamouc cell carcinoma
dc.subject DNA
dc.title Gene Therapy In Squamous Cell Carcinoma – A Short Review


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