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Diffusion limited field induced aggregation of magnetic liposomes

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dc.creator Licinio Pedro
dc.creator Frézard Frédéric
dc.date 2001
dc.date.accessioned 2013-05-30T01:01:46Z
dc.date.available 2013-05-30T01:01:46Z
dc.date.issued 2013-05-30
dc.identifier http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-97332001000300004
dc.identifier http://www.doaj.org/doaj?func=openurl&genre=article&issn=01039733&date=2001&volume=31&issue=3&spage=356
dc.identifier.uri http://koha.mediu.edu.my:8181/jspui/handle/123456789/3230
dc.description Magnetic liposomes are spherical vesicles containing magnetic particles. Their practical interest relies in their potential use as "intelligent" drug delivery systems, with magnetic driving or targeting possibilities. In the presence of a field, the vesicles become magnetized and interact. A strong interaction leads to aggregation and could in extreme lead to undesirable clogging in physiological conditions. We investigated the formation of chain aggregates in liposome dispersions in the presence of magnetic fields by light scattering measurements. Data analysis showed that aggregation number increased linearly with elapsed time, as for ordinary isotropic colloid diffusion limited aggregation. The rate of aggregation increased with the field also linearly for low field strengths, and saturates at higher fields. These results are in contrast with measurements for the pure magnetic fluid, i.e., non-encapsulated magnetic particle dispersions.
dc.publisher Sociedade Brasileira de Física
dc.source Brazilian Journal of Physics
dc.title Diffusion limited field induced aggregation of magnetic liposomes


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