| dc.creator |
Bustelo, Xosé R. |
|
| dc.creator |
Sauzeau, Vincent |
|
| dc.creator |
Berenjeno, Inmaculada M. |
|
| dc.date |
2008-06-17T09:05:14Z |
|
| dc.date |
2008-06-17T09:05:14Z |
|
| dc.date |
2007-04 |
|
| dc.date.accessioned |
2017-01-31T01:42:13Z |
|
| dc.date.available |
2017-01-31T01:42:13Z |
|
| dc.identifier |
BioEssays 29(4): 356–370 (2007) |
|
| dc.identifier |
0265-9247 |
|
| dc.identifier |
PMC1971132 |
|
| dc.identifier |
http://hdl.handle.net/10261/5126 |
|
| dc.identifier |
10.1002/bies.20558 |
|
| dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10261/5126 |
|
| dc.description |
24 páginas, 5 figuras, 1 tabla.-- El pdf del artículo es el manuscrito de autor. |
|
| dc.description |
Rho/Rac proteins constitute a subgroup of the Ras superfamily of GTP hydrolases. Although originally implicated in the control of cytoskeletal events, it is currently known that these GTPases coordinate diverse cellular functions, including cell polarity, vesicular trafficking, the cell cycle and transcriptomal dynamics. In this review, we will provide an overview on the recent advances in this field regarding the mechanism of regulation and signaling, and the roles in vivo of this important GTPase family. |
|
| dc.description |
Funding agencies: XRB’s work is supported by grants from the US National Cancer Institute (5R01-CA73735-10),
the Spanish Ministry of Education and Science (SAF2003-00028), the Castilla-León Autonomous Government
(SA053A05), and the Red Temática de Investigación Cooperativa en Cáncer (RD06/0020/0001, Spanish Ministry of
Health). VS was supported by an EMBO long term postdoctoral fellowship. IMB was partially supported by a Spanish
Ministry of Education and Science FPU fellowship (FP2000-6489). The Centro de Investigación del Cáncer is
supported by endowments from the CSIC, University of Salamanca, Castilla-León Autonomous Government, the Red
Temática de Investigacián Cooperativa de Centros de Cáncer (C03/10, Spanish Ministry of Health), and the Foundation
for Cancer Research of Salamanca. |
|
| dc.description |
Peer reviewed |
|
| dc.format |
25077 bytes |
|
| dc.format |
application/pdf |
|
| dc.language |
eng |
|
| dc.publisher |
Wiley-VCH |
|
| dc.relation |
http://dx.doi.org/10.1002/bies.20558 |
|
| dc.rights |
openAccess |
|
| dc.title |
GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo |
|
| dc.type |
Artículo |
|