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SOS-Independent Induction of dinB Transcription by β-Lactam-Mediated Inhibition of Cell Wall Synthesis in Escherichia coli

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dc.creator Pérez-Capilla, Tatiana
dc.creator Baquero, María del Rosario
dc.creator Gómez-Gómez, José María
dc.creator Ionel, Alina
dc.creator Martín, Soledad
dc.creator Blázquez, Jesús
dc.date 2008-06-13T12:26:47Z
dc.date 2008-06-13T12:26:47Z
dc.date 2005-02
dc.date.accessioned 2017-01-31T01:41:26Z
dc.date.available 2017-01-31T01:41:26Z
dc.identifier Journal of Bacteriology 187(4): 1515–1518 (2005)
dc.identifier 1098-5530
dc.identifier http://hdl.handle.net/10261/5097
dc.identifier 10.1128/JB.187.4.1515-1518.2005
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10261/5097
dc.description Transcription of the dinB gene, encoding DNA polymerase IV, is induced by the inhibition of cell wall synthesis at different levels. Using the β-lactam antibiotic ceftazidime, a PBP3 inhibitor, as a model, we have shown that this induction is independent of the LexA/RecA regulatory system. Induction of dinB transcription mediated by ceftazidime produces an increase in the reversion of a +1 Lac frameshift mutation.
dc.description Peer reviewed
dc.format 25073 bytes
dc.format application/pdf
dc.language eng
dc.publisher American Society for Microbiology
dc.relation http://dx.doi.org/10.1128/JB.187.4.1515-1518.2005
dc.rights closedAccess
dc.title SOS-Independent Induction of dinB Transcription by β-Lactam-Mediated Inhibition of Cell Wall Synthesis in Escherichia coli
dc.type Artículo


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