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Discovery of Inhibitors of Protein-Protein Interactions from Combinatorial Libraries

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dc.creator Vicent, María J.
dc.creator Pérez-Payá, Enrique
dc.creator Orzáez, Mar
dc.date 2008-05-19T10:10:17Z
dc.date 2008-05-19T10:10:17Z
dc.date 2007-01
dc.date.accessioned 2017-01-31T01:22:01Z
dc.date.available 2017-01-31T01:22:01Z
dc.identifier Curr Top Med Chem 7 (1): 83-95
dc.identifier http://hdl.handle.net/10261/4336
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10261/4336
dc.description The definitive version is available at http://www.bentham.org/ctmc/index.htm
dc.description Protein-protein interactions play a central role within numerous processes in the cell. The relevance of the processes in which this type of interactions are implicated make them responsible for many pathological situations. In the last decade protein-protein interfaces have shown their potential as new drug targets, and combinatorial chemistry has been defined as a useful tool in this line. This review gives a global vision of the actual situation of combinatorial chemistry, highlighting its applicability to high-throughput drug discovery and giving some crucial examples of its contribution to find modulators of protein-protein interactions
dc.description Peer reviewed
dc.format 118239 bytes
dc.format application/pdf
dc.language eng
dc.publisher Bentham Science Publishers
dc.rights openAccess
dc.title Discovery of Inhibitors of Protein-Protein Interactions from Combinatorial Libraries
dc.type Artículo


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