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Polarization of both major body axes in Drosophila by gurken-torpedo signalling

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dc.creator González-Reyes, Acaimo
dc.creator Elliott, Heather
dc.creator St Johnston, Daniel
dc.date 2008-05-07T15:36:08Z
dc.date 2008-05-07T15:36:08Z
dc.date 1995-06-22
dc.date.accessioned 2017-01-31T01:11:42Z
dc.date.available 2017-01-31T01:11:42Z
dc.identifier Nature 375, 654-658 (1995)
dc.identifier 0028-0836
dc.identifier http://hdl.handle.net/10261/4076
dc.identifier 10.1038/375654a0
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10261/4076
dc.description Final full-text version of this paper available at: http://dx.doi.org/10.1038/375654a0
dc.description Anterior–posterior polarity in Drosophila arises from the movement of the oocyte to the posterior of the egg chamber, and the subsequent acquisition of posterior fate by the adjacent somatic follicle cells. We demonstrate that gurken is necessary in the oocyte and torpedo/DER in the follicle cells for the induction of posterior fate. As the gurken–torpedo/DER pathway also establishes dorsoventral polarity later in oogenesis, Drosophila uses the same germline to same signalling pathway to determine both embryonic axes.
dc.description A.G.-R. was a European Molecular Biology Organisation postdoctoral fellow. This work was supported by a Wellcome Trust Senior Fellowship (D.StJ.) and a European Community Postdoctoral Fellowship (A.G.-R.)
dc.description Peer reviewed
dc.format 22195 bytes
dc.format application/pdf
dc.language eng
dc.publisher Nature Publishing Group
dc.rights openAccess
dc.subject Anterior-posterior polarity
dc.subject Drosophila oocytes
dc.subject Signaling
dc.subject Development Biology
dc.title Polarization of both major body axes in Drosophila by gurken-torpedo signalling
dc.type Artículo


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