| dc.contributor |
Ministerio de Educación y Ciencia (España) |
|
| dc.contributor |
Comisión Interministerial de Ciencia y Tecnología, CICYT (España) |
|
| dc.contributor |
European Commission |
|
| dc.creator |
Rey, Manuel |
|
| dc.creator |
Ohno, Susumu |
|
| dc.creator |
Pintor-Toro, José Antonio |
|
| dc.creator |
Llobell, Antonio |
|
| dc.creator |
Benítez, Tahia |
|
| dc.date |
2008-04-14T11:05:06Z |
|
| dc.date |
2008-04-14T11:05:06Z |
|
| dc.date |
1998-05 |
|
| dc.date.accessioned |
2017-01-31T01:02:17Z |
|
| dc.date.available |
2017-01-31T01:02:17Z |
|
| dc.identifier |
Proceedings of the National Academy of Sciences of the United States of America 95(11): 6212–6216 (1998) |
|
| dc.identifier |
1091-6490 |
|
| dc.identifier |
http://hdl.handle.net/10261/3564 |
|
| dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10261/3564 |
|
| dc.description |
5 páginas, 4 figuras. |
|
| dc.description |
A gene, qid74, of mycoparasitic filamentous fungus Trichoderma harzianum and its allies encodes a cell wall protein that is induced by replacing glucose in the culture medium with chitin (simulated mycoparasitism conditions). Because no trace of this gene can be detected in related species such as Gibberella fujikuroi and Saccharomyces cerevisiae, the qid74 gene appears to have arisen de novo within the genus Trichoderma. Qid74 protein, 687 residues long, is now seen as highly conserved tandem repeats of the 59-residue-long unit. This unit itself, however, may have arisen as tandem repeats of the shorter 13-residue-long basic unit. Within the genus Trichoderma, the amino acid sequence of Qid74 proteins has been conserved in toto. The most striking is the fact that Qid74 shares 25.3% sequence identity with the carboxyl-terminal half of the 1,572-residue-long BR3 protein of the dipteran insect Chironomus tentans. BR3 protein is secreted by the salivary gland of each aquatic larva of Chironomus to form a tube to house itself. Furthermore, the consensus sequence derived from these 59-residue-long repeating units resembles those of epidermal growth factor-like domains found in divergent invertebrate and vertebrate proteins as to the positions of critical cysteine residues and homology of residues surrounding these cysteines. |
|
| dc.description |
M.R. was the recipient of a postgraduate fellowship from the Ministerio de Educación y Ciencia. This work was supported by Grants BIO94-0289 and TS3-CT92-0140 from the Comisión Interministerial de Ciencia y Tecnología and the European Commission, respectively. |
|
| dc.description |
Peer reviewed |
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| dc.format |
357518 bytes |
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| dc.format |
application/pdf |
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| dc.language |
eng |
|
| dc.publisher |
National Academy of Sciences (U.S.) |
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| dc.rights |
closedAccess |
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| dc.title |
Unexpected homology between inducible cell wall protein QID74 of filamentous fungi and BR3 salivary protein of the insect Chironomus |
|
| dc.type |
Artículo |
|