| dc.creator |
Ponce, Carlos |
|
| dc.creator |
Ponce, Elisa |
|
| dc.creator |
Vinelli, Elizabeth |
|
| dc.creator |
Montoya, Alberto |
|
| dc.creator |
Aguilar, Vilma de |
|
| dc.creator |
González, Antonio Gustavo |
|
| dc.creator |
Zingales, Bianca |
|
| dc.creator |
Rangel-Aldao, Rafael |
|
| dc.creator |
Levin, Mariano J. |
|
| dc.creator |
Esfandiari, Javan |
|
| dc.creator |
Umezawa, Eufrosina S. |
|
| dc.creator |
Luquetti, Alejandro O. |
|
| dc.creator |
Silveira, José Franco da |
|
| dc.date |
2008-04-03T09:13:25Z |
|
| dc.date |
2008-04-03T09:13:25Z |
|
| dc.date |
2005-10 |
|
| dc.date.accessioned |
2017-01-31T01:01:27Z |
|
| dc.date.available |
2017-01-31T01:01:27Z |
|
| dc.identifier |
J Clin Microbiol. 2005 October; 43(10): 5065–5068 |
|
| dc.identifier |
1098-660X |
|
| dc.identifier |
http://hdl.handle.net/10261/3431 |
|
| dc.identifier |
10.1128/JCM.43.10.5065-5068.2005 |
|
| dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10261/3431 |
|
| dc.description |
In this study we compared the performance of the Chagas Stat-Pak rapid immunochromatographic test with
a standard enzyme-linked immunosorbent assay (ELISA) in the serodiagnosis of Chagas’ disease in Central
America. Out of 3,400 blood donor samples, 156 (4.6%) were positive in both assays. Three sera out of 2,084
samples from reference laboratories were negative with the rapid test but positive with the ELISA (99.8%
agreement). Agreement of 100% between the two tests was observed with 339 additional sera from patients with
cardiopathies and 175 sera from potential blood donors in emergency surgical cases occurring on weekends or
at night. In conclusion, Chagas Stat-Pak showed 99.6% and 99.9% sensitivity and specificity, respectively, when
assayed with 5,998 serum samples. It is a sensitive and specific alternative to the ELISA, as required in medical
emergencies and blood screenings in Central America. |
|
| dc.description |
This study was supported by grants from the CYTED (Iberoamerican
Biotechnology Project, Spain), CNPq and FAPESP (Brazil), and the PAHO/WHO Regional Office for the Americas/Pan American
Sanitary Bureau (Washington, D.C.). |
|
| dc.description |
Peer reviewed |
|
| dc.format |
51901 bytes |
|
| dc.format |
application/pdf |
|
| dc.language |
eng |
|
| dc.publisher |
American Society for Microbiology |
|
| dc.rights |
openAccess |
|
| dc.title |
Validation of a Rapid and Reliable Test for Diagnosis of Chagas' Disease by Detection of Trypanosoma cruzi-Specific Antibodies in Blood of Donors and Patients in Central America |
|
| dc.type |
Artículo |
|