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Mini-Review: Factors Affecting Multiple Invasions of Erythrocytes in Plasmodium and other Malaria-like Parasites. A Neglected Characteristic of Infections

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dc.creator Martínez de la Puente, Josué
dc.creator Merino, Santiago
dc.date 2008-03-27T17:01:34Z
dc.date 2008-03-27T17:01:34Z
dc.date 2008-03-27T17:01:34Z
dc.date.accessioned 2017-01-31T01:01:18Z
dc.date.available 2017-01-31T01:01:18Z
dc.identifier 1874-4214
dc.identifier http://hdl.handle.net/10261/3344
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10261/3344
dc.description Multiple invasions (MIs) are produced when the same erythrocyte is infected by more than one parasite cell. These MIs commonly occur in different haemosporidia species including Plasmodium and other malaria-like parasites. However, the frequency of MIs has been traditionally considered in studies both in vivo and in vitro as an artefact produced by high parasite densities, leading most researchers to think that MIs does not have a true biological meaning but they are merely the product of chance. Other proposed explanations for the occurrence of MIs include an adaptive host strategy to reduce parasite damage and hinder parasite transmission success and an adaptive parasite strategy which favours parasite transmission success. Here we review the relevant literature supporting or rejecting these hypotheses proposed to explain the occurrence of MIs. Although the possibility that MIs being due to higher parasite densities has received much support, more studies are clearly necessary to reveal the potential importance of host defences and parasite strategies on the occurrence of MIs in nature.
dc.description Ministerio de Educación y Ciencia. Proyecto CGL 2006-14129-C02-01.
dc.description Peer reviewed
dc.format 62996 bytes
dc.format application/pdf
dc.language eng
dc.relation The Open Parasitology Journal
dc.relation 2
dc.rights openAccess
dc.subject Haemoproteus
dc.subject Leucocytozoon
dc.subject Malaria
dc.subject Host-parasite interactions
dc.subject Transmission
dc.title Mini-Review: Factors Affecting Multiple Invasions of Erythrocytes in Plasmodium and other Malaria-like Parasites. A Neglected Characteristic of Infections
dc.type Artículo


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