| dc.creator |
Capelo, José Luis |
|
| dc.creator |
Vázquez, Jesús |
|
| dc.creator |
López-Ferrer, Daniel |
|
| dc.creator |
Moura, Isabel |
|
| dc.date |
2008-03-19T10:14:39Z |
|
| dc.date |
2008-03-19T10:14:39Z |
|
| dc.date |
2007-01-18 |
|
| dc.date.accessioned |
2017-01-31T01:00:48Z |
|
| dc.date.available |
2017-01-31T01:00:48Z |
|
| dc.identifier |
International Publication Number: WO 2007/007267 A2 |
|
| dc.identifier |
http://hdl.handle.net/10261/3254 |
|
| dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10261/3254 |
|
| dc.description |
Filing Date: 2006-07-07.-- Priority Data: PT 103303 (2005-07-07) |
|
| dc.description |
The present invention refers to an acceleration process for macromolecular fragmentation in liquid medium, in gel or in a solid support, by means of joint application of enzymes and ultrasounds, as well as isotopes. The macromolecules, in any of these liquids, are mixed with enzymes and inserted in a recipient (2) and exposed to an ultrasonic radiation field (1). The combined effect of the enzymes and of the ultrasounds allows accomplishing, in time ranges between 10 s and 600 s, the fragmentation of macromolecules or whole proteomes, with the correspondent formation of their constituent lower molecular units. |
|
| dc.format |
392905 bytes |
|
| dc.format |
application/pdf |
|
| dc.language |
eng |
|
| dc.rights |
openAccess |
|
| dc.title |
Selective acceleration process for macromolecular fragmentation through joint application of enzymes and ultrasounds |
|
| dc.type |
Patente |
|