| dc.creator |
Sánchez García, Isidro |
|
| dc.creator |
Voces, Felipe |
|
| dc.creator |
Pérez-Mancera, P. A. |
|
| dc.date |
2008-03-18T16:49:41Z |
|
| dc.date |
2008-03-18T16:49:41Z |
|
| dc.date |
2007-02-01 |
|
| dc.date.accessioned |
2017-01-31T01:00:48Z |
|
| dc.date.available |
2017-01-31T01:00:48Z |
|
| dc.identifier |
International Publication Number: WO 2007/012970 A1 |
|
| dc.identifier |
http://hdl.handle.net/10261/3252 |
|
| dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10261/3252 |
|
| dc.description |
Filing Date: 2006-07-28.- Priority Data: EP 05076753.2 (2005-07-28). |
|
| dc.description |
The invention relates to the graded expression level of SNAIL gene or its expression products, as a marker of the capacity of epithelial and mesenchymal tumours and/or cancers for disseminating to other tissues or organs. The invention further relates to a transgenic non-human mammal comprising in its genome a transgene that comprises a nucleic acid sequence encoding the SNAIL protein, and the use of SNAIL as a marker of epithelial and mesenchymal tumours and/or cancers as well as in DNA damage-based diseases In addition, the invention relates to the use of SNAIL as a therapeutic and diagnostic target for said pathologies. |
|
| dc.description |
Peer reviewed |
|
| dc.format |
4417828 bytes |
|
| dc.format |
application/pdf |
|
| dc.language |
eng |
|
| dc.rights |
openAccess |
|
| dc.subject |
SNAIL gene |
|
| dc.subject |
Tumours |
|
| dc.subject |
Transgenic non-human mammal |
|
| dc.subject |
SNAIL protein |
|
| dc.subject |
Cancer |
|
| dc.subject |
Biological Markers |
|
| dc.title |
Graded expression of SNAIL as marker of cancer development and DNA damage-based diseases |
|
| dc.type |
Patente |
|