أعرض تسجيلة المادة بشكل مبسط
| dc.creator |
Soriano, Francisco |
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| dc.creator |
Rodríguez-Cerrato, Violeta |
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| dc.creator |
García, Pedro |
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| dc.creator |
Huelves, Lorena |
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| dc.creator |
García, Ernesto |
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| dc.creator |
Prado, Gema del |
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| dc.creator |
Gracia, Matilde |
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| dc.creator |
Ponte, Carmen |
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| dc.creator |
López, Rubens |
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| dc.date |
2008-02-06T12:32:45Z |
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| dc.date |
2008-02-06T12:32:45Z |
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| dc.date |
2007-06-18 |
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| dc.date.accessioned |
2017-01-31T00:59:58Z |
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| dc.date.available |
2017-01-31T00:59:58Z |
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| dc.identifier |
Antimicrob Agents Chemother. 2007 September; 51(9): 3371–3373 |
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| dc.identifier |
PMCID: 2043201 |
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| dc.identifier |
0066-4804 |
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| dc.identifier |
http://hdl.handle.net/10261/2875 |
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| dc.identifier |
10.1128/AAC.00137-07 |
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| dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10261/2875 |
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| dc.description |
The in vitro and in vivo antipneumococcal activities of the main pneumococcal autolysin (LytA) and Cpl-1, a lysozyme encoded by phage Cp-1, were studied. Intraperitoneal therapy with LytA or high-dose Cpl-1 remarkably reduced peritoneal bacterial counts (>5 log10 CFU/ml) compared with those for the controls. After intravenous injection, LytA was the most effective treatment. |
|
| dc.description |
This research was supported by grants from the Red Tematica de Investigacion Cooperativa Spanish Pneumococcal Infection Study Network (grant G03/103) (Ministerio de Sanidad y Consumo, Spain) and the program COMBACT Nuevas Dianas para Combatir a las Bacterias Patogenas (grant S-BIO-026-2006) (Consejerıa de Educacion, Comunidad de Madrid, Madrid, Spain). L.H. and G.D.P. received scholarships from the Fundacio´n Conchita Ra´bago; M.G. received a
scholarship from the Fondo de Investigaciones Sanitarias, Ministerio
de Sanidad y Consumo, Spain. |
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| dc.description |
Peer reviewed |
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| dc.format |
71359 bytes |
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| dc.format |
application/pdf |
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| dc.language |
eng |
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| dc.publisher |
American Society for Microbiology |
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| dc.rights |
closedAccess |
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| dc.title |
Pneumococcal LytA Autolysin, a Potent Therapeutic Agent in Experimental Peritonitis-Sepsis Caused by Highly β-Lactam-Resistant Streptococcus pneumoniae |
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| dc.type |
Artículo |
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