| dc.creator |
Quintana Rodríguez, Carmen |
|
| dc.date |
2008-02-04T13:39:03Z |
|
| dc.date |
2008-02-04T13:39:03Z |
|
| dc.date |
2008-02-04T13:39:03Z |
|
| dc.date.accessioned |
2017-01-31T00:59:55Z |
|
| dc.date.available |
2017-01-31T00:59:55Z |
|
| dc.identifier |
Mini Rev Med Chem. 2007 Sep;7(9):961-75 |
|
| dc.identifier |
PMID: 17897084 |
|
| dc.identifier |
http://hdl.handle.net/10261/2831 |
|
| dc.identifier |
10.2174/138955707781662654 |
|
| dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10261/2831 |
|
| dc.description |
PMID: 17897084 [PubMed - indexed for MEDLINE] |
|
| dc.description |
Using analytical microscopies we have observed an increase of Fe(2+) iron-induced oxidative stress inside pathological ferritin (Ft). This finding, together with the presence of Ft in myelinated axons associated with oligodendrocyte processes and myelin sheet fraying, suggests that a dysfunction of ferritin (a ferritinopathy) may be the non-specific aging-dependent pathogenic event responsible for neurodegenerative disease. |
|
| dc.description |
Peer reviewed |
|
| dc.format |
24576 bytes |
|
| dc.format |
application/msword |
|
| dc.language |
eng |
|
| dc.relation |
http://dx.doi.org/10.2174/138955707781662654 |
|
| dc.rights |
closedAccess |
|
| dc.subject |
Ferritinopathy |
|
| dc.subject |
Neuropathology |
|
| dc.subject |
Alzheimer |
|
| dc.subject |
Analytical microscopies |
|
| dc.subject |
NanoSIMS |
|
| dc.title |
Contribution of analytical microscopies to human neurodegenerative diseases research (PSP and AD). |
|
| dc.type |
Artículo |
|