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A study of polymer-supported bases for the solution phase synthesis of glycosyl trichloroacetimidates

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dc.creator Chiara, José Luis
dc.creator Encinas, Lourdes
dc.creator Díaz, Beatriz
dc.date 2007-11-08T17:01:20Z
dc.date 2007-11-08T17:01:20Z
dc.date 2005-04-04
dc.date.accessioned 2017-01-31T00:58:17Z
dc.date.available 2017-01-31T00:58:17Z
dc.identifier Tetrahedron Letters 46, 14 (2005), pp. 2445-2448
dc.identifier 0040-4039
dc.identifier http://hdl.handle.net/10261/1978
dc.identifier 10.1016/j.tetlet.2005.02.055
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10261/1978
dc.description Polystyrene-supported strong organic bases are highly efficient reagents for the solution-phase synthesis of glycosyl trichloroacetimidates, affording quantitative yields of pure products in short reaction times after simple filtration and evaporation. Although efficiency of the different bases varies with substrate structure, polymer-bound 1,8-diazabicyclo[5.4.0]undec-7-ene was found to give the best results for all substrates tested.
dc.description We thank the Ministry of Education and Science of Spain for financial support (projects BQU2000-1501-C02-01 and BQU2003-03550-C03-02) and a predoctoral fellowship to L.E.
dc.description Peer reviewed
dc.language eng
dc.publisher Elsevier
dc.rights closedAccess
dc.subject Carbohydrates
dc.subject Solid-supported reagents
dc.subject Glycosylation
dc.title A study of polymer-supported bases for the solution phase synthesis of glycosyl trichloroacetimidates
dc.type Artículo


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