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Mortality reduction associated with HIV/AIDS care and antiretroviral treatment in rural Malawi: evidence from registers, coffin sales and funerals.

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dc.contributor Thyolo District Health Services, Ministry of Health and Population, Thyolo, Malawi.
dc.creator Mwagomba, Beatrice
dc.creator Zachariah, Rony
dc.creator Massaquoi, Moses
dc.creator Misindi, Dalitso
dc.creator Manzi, Marcel
dc.creator Mandere, Bester C
dc.creator Bemelmans, Marielle
dc.creator Philips, Mit
dc.creator Kamoto, Kelita
dc.creator Schouten, Eric J
dc.creator Harries, A D
dc.date 2010-05
dc.date.accessioned 2017-01-31T07:17:41Z
dc.date.available 2017-01-31T07:17:41Z
dc.identifier Mortality reduction associated with HIV/AIDS care and antiretroviral treatment in rural Malawi: evidence from registers, coffin sales and funerals. 2010, 5 (5):e10452 PLoS ONE
dc.identifier 1932-6203
dc.identifier 20454611
dc.identifier 10.1371/journal.pone.0010452
dc.identifier http://hdl.handle.net/10144/99348
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/99348
dc.identifier PloS One
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/99348
dc.description BACKGROUND: To report on the trend in all-cause mortality in a rural district of Malawi that has successfully scaled-up HIV/AIDS care including antiretroviral treatment (ART) to its population, through corroborative evidence from a) registered deaths at traditional authorities (TAs), b) coffin sales and c) church funerals. METHODS AND FINDINGS: Retrospective study in 5 of 12 TAs (covering approximately 50% of the population) during the period 2000-2007. A total of 210 villages, 24 coffin workshops and 23 churches were included. There were a total of 18,473 registered deaths at TAs, 15781 coffins sold, and 2762 church funerals. Between 2000 and 2007, there was a highly significant linear downward trend in death rates, sale of coffins and church funerals (X(2) for linear trend: 338.4 P<0.0001, 989 P<0.0001 and 197, P<0.0001 respectively). Using data from TAs as the most reliable source of data on deaths, overall death rate reduction was 37% (95% CI:33-40) for the period. The mean annual incremental death rate reduction was 0.52/1000/year. Death rates decreased over time as the percentage of people living with HIV/AIDS enrolled into care and ART increased. Extrapolating these data to the entire district population, an estimated 10,156 (95% CI: 9786-10259) deaths would have been averted during the 8-year period. CONCLUSIONS: Registered deaths at traditional authorities, the sale of coffins and church funerals showed a significant downward trend over a 8-year period which we believe was associated with the scaling up HIV/AIDS care and ART.
dc.language en
dc.rights Published by Public Library of Science, [url]http://www.plosone.org/[/url] Archived on this site by Open Access permission
dc.title Mortality reduction associated with HIV/AIDS care and antiretroviral treatment in rural Malawi: evidence from registers, coffin sales and funerals.


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