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Development of dual-class antiretroviral drug resistance in a child coinfected with HIV and tuberculosis: a case report from KwaZulu-Natal, South Africa.

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dc.contributor Massachusetts General Hospital, and Brigham and Women's Hospital, Boston, MA, USA. richard.murphy@newyork.msf.org
dc.creator Murphy, R A
dc.creator France, H
dc.creator Sunpath, H
dc.creator Gordon, M L
dc.creator Marconi, V
dc.creator Kuritzkes, D R
dc.creator McIntosh, K
dc.date 2009-02
dc.date.accessioned 2017-01-31T07:14:24Z
dc.date.available 2017-01-31T07:14:24Z
dc.identifier Development of dual-class antiretroviral drug resistance in a child coinfected with HIV and tuberculosis: a case report from KwaZulu-Natal, South Africa. 2009, 55 (1):60-2 J. Trop. Pediatr.
dc.identifier 1465-3664
dc.identifier 18786985
dc.identifier 10.1093/tropej/fmn074
dc.identifier http://hdl.handle.net/10144/71895
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/71895
dc.identifier Journal of Tropical Pediatrics
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/71895
dc.description The treatment of concurrent HIV and tuberculosis (TB) in children <3 years of age has not been well-studied and is complicated by potential drug-drug interactions. The recommended antiretroviral therapy (ART) in coinfected children in South Africa consists of full-strength ritonavir, lamivudine and stavudine. We report on a child initiated on this regimen, during concurrent TB treatment, who promptly developed an adverse reaction, virologic failure and dual-class antiretroviral drug resistance, compromising subsequent salvage ART.
dc.language en
dc.publisher Published by Oxford University Press
dc.relation http://tropej.oxfordjournals.org/cgi/content/abstract/55/1/60
dc.rights Published by Oxford University Press Archived on this site with kind permission from Oxford University Press
dc.title Development of dual-class antiretroviral drug resistance in a child coinfected with HIV and tuberculosis: a case report from KwaZulu-Natal, South Africa.


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