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Biological diagnosis of meningococcal meningitis in the African meningitis belt: current epidemic strategy and new perspectives.

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dc.contributor CERMES, Réseau International Institut Pasteur, PO Box 10887, Niamey, Niger. schanteau@cermes.org
dc.creator Chanteau, S
dc.creator Rose, A
dc.creator Djibo, S
dc.creator Nato, F
dc.creator Boisier, P
dc.date 2007-09-03
dc.date.accessioned 2017-01-31T07:13:44Z
dc.date.available 2017-01-31T07:13:44Z
dc.identifier Biological diagnosis of meningococcal meningitis in the African meningitis belt: current epidemic strategy and new perspectives. 2007, 25 Suppl 1:A30-6 Vaccine
dc.identifier 0264-410X
dc.identifier 17517452
dc.identifier 10.1016/j.vaccine.2007.04.037
dc.identifier http://hdl.handle.net/10144/56173
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/56173
dc.identifier Vaccine
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/56173
dc.description Laboratory diagnosis is an essential component in surveillance of meningococcal epidemics, as it can inform decision-makers of the Neisseria meningitidis serogroup(s) involved and the most appropriate vaccine to be selected for mass vaccination. However, countries most affected face real limitations in laboratory diagnostics, due to lack of resources. We describe current diagnostic tools and examine their cost-effectiveness for use in an epidemic context. The conclusion is that current WHO recommendations to use only the latex agglutination assay (Pastorex) at epidemic onset is cost-effective, but recently developed rapid diagnostic tests for the major epidemic-causing meningococcal serogroups may prove a breakthrough for the future.
dc.language en
dc.publisher Elsevier
dc.relation http://www.sciencedirect.com/science/journal/0264410X
dc.rights Published by Elsevier Archived on this site with kind permission and copyright 2007 from Elsevier
dc.title Biological diagnosis of meningococcal meningitis in the African meningitis belt: current epidemic strategy and new perspectives.
dc.type Article


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