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Efficacy and safety of dihydroartemisinin-piperaquine.

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dc.contributor Faculty of Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Bangkok 10400, Thailand.
dc.creator Myint, H Y
dc.creator Ashley, E A
dc.creator Day, N P J
dc.creator Nosten, F
dc.creator White, N J
dc.date 2007-09
dc.date.accessioned 2017-01-31T07:13:39Z
dc.date.available 2017-01-31T07:13:39Z
dc.identifier Efficacy and safety of dihydroartemisinin-piperaquine. 2007, 101 (9):858-66 Trans. R. Soc. Trop. Med. Hyg.
dc.identifier 0035-9203
dc.identifier 17659311
dc.identifier 10.1016/j.trstmh.2007.05.018
dc.identifier http://hdl.handle.net/10144/52374
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/52374
dc.identifier Transactions of the Royal Society of Tropical Medicine and Hygiene
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/52374
dc.description Dihydroartemisinin-piperaquine, a fixed-dose combination antimalarial, is an inexpensive, safe and highly effective treatment for uncomplicated falciparum or vivax malaria. Efficacy assessed over 28-63 days has consistently exceeded 95% in the treatment of multidrug-resistant falciparum malaria. More than 2600 patients have been treated with this combination in prospective studies, mainly in Southeast Asia. Tolerability was uniformly good, and no serious adverse effects have been identified. The dosing regimen has been simplified from four doses to once daily over 3 days. More information on efficacy in Africa, and more pharmacokinetic and efficacy data in children are needed.
dc.language en
dc.publisher Elsevier
dc.relation http://www.sciencedirect.com/science/journal/00359203
dc.rights Published by Elsevier Archived on this site with the kind permission of Elsevier Ltd. ([url]http://www.sciencedirect.com/science/journal/00359203[/url]) and the Royal Society of Tropical Medicine and Hygiene ([url]http://www.rstmh.org/transactions.asp[/url])
dc.title Efficacy and safety of dihydroartemisinin-piperaquine.
dc.type Article

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