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HIV-1 viral load monitoring: an opportunity to reinforce treatment adherence in a resource-limited setting in Thailand.

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dc.contributor Médecins Sans Frontières, 28/36 Chokchai 4 Road, Ladphrao, Bangkok 10230, Thailand.
dc.creator Wilson, D
dc.creator Keiluhu, A K
dc.creator Kogrum, S
dc.creator Reid, T
dc.creator Seriratana, N
dc.creator Ford, N
dc.creator KyawKyaw, M K
dc.creator Talangsri, P
dc.creator Taochalee, N
dc.date 2008-12-23
dc.date.accessioned 2017-01-31T07:13:06Z
dc.date.available 2017-01-31T07:13:06Z
dc.identifier HIV-1 viral load monitoring: an opportunity to reinforce treatment adherence in a resource-limited setting in Thailand. 2008: Trans. R. Soc. Trop. Med. Hyg.
dc.identifier 0035-9203
dc.identifier 19110288
dc.identifier 10.1016/j.trstmh.2008.11.007
dc.identifier http://hdl.handle.net/10144/48833
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/48833
dc.identifier Transactions of the Royal Society of Tropical Medicine and Hygiene
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/48833
dc.description This paper describes a program to increase patients' treatment literacy regarding viral load (VL) monitoring through patient education materials and a counseling protocol, implemented by peer counselors, in order to reinforce adherence to first-line treatment. VL monitoring and second-line antiretroviral treatment were introduced into an established first-line treatment program in a rural district hospital in Thailand. All patients (171 adults and 14 children) taking antiretroviral treatment for more than 6 months participated and those with detectable VL were targeted for additional adherence support. The main outcome measure recorded was the number of detectable results becoming undetectable after counseling. Four adults and one child had a persistently high VL and switched to second-line treatment. Of 51 adults (30%) with an initial low detectable VL, 47/51 identified likely explanations, usually linked with poor adherence. Following counseling, VL became undetectable in 45/51 cases and some patients could resolve long-standing psychosocial problems. We conclude that HIV-1 VL monitoring together with targeted counseling for patients with detectable VL can promote adherence to treatment, providing an opportunity to delay onset of HIV-1 resistance. When implemented with a patient-centered approach, it can be a very useful tool for psychosocial support.
dc.language en
dc.rights Published by Elsevier Archived on this site with the kind permission of Elsevier Ltd. ([url]http://www.sciencedirect.com/science/journal/00359203[/url]) and the Royal Society of Tropical Medicine and Hygiene ([url]http://www.rstmh.org/transactions.asp[/url])
dc.title HIV-1 viral load monitoring: an opportunity to reinforce treatment adherence in a resource-limited setting in Thailand.


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