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The emerging crisis of drug-resistant tuberculosis in South Africa: lessons from New York City.

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dc.contributor Division of Infectious Diseases, Massachusetts General Hospital and Brigham and Women's Hospital, Boston, Massachusetts, USA. richard.murphy@newyork.msf.org
dc.creator Murphy, R A
dc.date 2008-06-01
dc.date.accessioned 2017-01-31T07:12:56Z
dc.date.available 2017-01-31T07:12:56Z
dc.identifier The emerging crisis of drug-resistant tuberculosis in South Africa: lessons from New York City. 2008, 46 (11):1729-32 Clin. Infect. Dis.
dc.identifier 1537-6591
dc.identifier 18426372
dc.identifier 10.1086/587903
dc.identifier http://hdl.handle.net/10144/41794
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/41794
dc.identifier Clinical Infectious Diseases
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/41794
dc.description Multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis have emerged as important infections in South Africa among patients infected with human immunodeficiency virus (HIV). In the face of this new epidemic, South Africa must rededicate itself to the task of tuberculosis control and treatment with a rapid, multifaceted approach. Priorities include expansion of second-line treatment capacity, investment in clinical laboratories, a system to ensure supervised treatment for all patients, and enhancement of infection control procedures. In New York City, where drug-resistant tuberculosis emerged 2 decades ago--also in the context of a large HIV-infected population and an underfunded public health infrastructure--similar steps were successful in leading to the rapid decrease in rates of drug resistance among tuberculosis isolates. With refinements based on local resource constraints, urgent measures could potentially arrest the alarming increase in multidrug-resistant and extensively drug-resistant tuberculosis cases in South Africa. Unlike many countries in sub-Saharan Africa, South Africa has the capacity to mount a rapid and large-scale response before drug-resistant tuberculosis envelops a much larger and far poorer region.
dc.language en
dc.rights Archived with thanks to Clinical Infectious Diseases : an official publication of the Infectious Diseases Society of America
dc.title The emerging crisis of drug-resistant tuberculosis in South Africa: lessons from New York City.


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