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Rapid culture-based methods for drug-resistance detection in Mycobacterium tuberculosis.

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dc.contributor Mycobacteriology Unit, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium.
dc.creator Palomino, J C
dc.creator Martin, A
dc.creator Von Groll, A
dc.creator Portaels, F
dc.date 2008-10
dc.date.accessioned 2017-01-31T07:12:38Z
dc.date.available 2017-01-31T07:12:38Z
dc.identifier Rapid culture-based methods for drug-resistance detection in Mycobacterium tuberculosis. 2008, 75 (2):161-6 J. Microbiol. Methods
dc.identifier 0167-7012
dc.identifier 18627779
dc.identifier 10.1016/j.mimet.2008.06.015
dc.identifier http://hdl.handle.net/10144/39615
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/39615
dc.identifier Journal of Microbiological Methods
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/39615
dc.description Tuberculosis still represents a major public health problem, especially in low-resource countries where the burden of the disease is more important. Multidrug-resistant and extensively drug drug-resistant tuberculosis constitute serious problems for the efficient control of the disease stressing the need to investigate resistance to first- and second-line drugs. Conventional methods for detecting drug-resistance in Mycobacterium tuberculosis are slow and cumbersome. The most commonly used proportion method on Löwenstein-Jensen medium or Middlebrook agar requires a minimum of 3-4 weeks to produce results. Several new approaches have been proposed in the last years for the rapid and timely detection of drug-resistance in tuberculosis. This review will address phenotypic culture-based methods for rapid drug susceptibility testing in M. tuberculosis.
dc.language en
dc.publisher Elsevier
dc.relation http://www.sciencedirect.com/science/journal/01677012.
dc.rights Archived with kind thanks to Elsevier, copyright 2008.
dc.title Rapid culture-based methods for drug-resistance detection in Mycobacterium tuberculosis.


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