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Tuberculosis treatment in complex emergencies: are risks outweighing benefits?

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dc.contributor MSF Brussels
dc.creator Biot, M
dc.creator Chandramohan, D
dc.creator Porter, J D H
dc.date 2003-03
dc.date.accessioned 2017-01-31T07:12:40Z
dc.date.available 2017-01-31T07:12:40Z
dc.identifier Tuberculosis treatment in complex emergencies: are risks outweighing benefits? 2003, 8 (3):211-8 Trop. Med. Int. Health
dc.identifier 1360-2276
dc.identifier 12631310
dc.identifier http://hdl.handle.net/10144/39578
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/39578
dc.identifier Tropical Medicine & International Health
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/39578
dc.description Tuberculosis (TB) is a major public health problem in complex emergencies. Humanitarian agencies usually postpone the decision to offer TB treatment and opportunities to treat TB patients are often missed. This paper looks at the problem of tuberculosis treatment in these emergencies and questions whether treatment guidelines could be more flexible than international recommendations. A mathematical model is used to calculate the risks and benefits of different treatment scenarios with increasing default rates. Model outcomes are compared to a situation without treatment. An economic analysis further discusses the findings in a trade-off between the extra costs of treating relapses and failures and the savings in future treatment costs. In complex emergencies, if a TB programme could offer 4-month treatment for 75% of its patients, it could still be considered beneficial in terms of public health. In addition, the proportion of patients following at least 4 months of treatment can be used as an indicator to help evaluate the public health harm and benefit of the TB programme.
dc.language en
dc.rights Archived on this site with the kind permission of Wiley-Blackwell, [url]http://www.blackwell-synergy.com/loi/tmi[/url]
dc.title Tuberculosis treatment in complex emergencies: are risks outweighing benefits?


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