dc.contributor |
Department of Nuclear Medicine, Hĵpital Erasme, Université Libre de Bruxelles, Brussels, Belgium. rmorenor@ulb.ac.be |
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dc.creator |
Moreno-Reyes, R |
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dc.creator |
Suetens, C |
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dc.creator |
Mathieu, F |
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dc.creator |
Begaux, F |
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dc.creator |
Zhu, D |
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dc.creator |
Rivera, M |
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dc.creator |
Boelaert, M |
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dc.creator |
Nève, J |
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dc.creator |
Perlmutter, N |
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dc.creator |
Vanderpas, J |
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dc.date |
2001 |
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dc.date.accessioned |
2017-01-31T07:11:14Z |
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dc.date.available |
2017-01-31T07:11:14Z |
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dc.identifier |
Kashin-Beck disease and iodine deficiency in Tibet. 2001, 25 (3):164-6notInt Orthop |
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dc.identifier |
0341-2695 |
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dc.identifier |
11482533 |
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dc.identifier |
http://hdl.handle.net/10144/28678 |
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dc.identifier |
http://fieldresearch.msf.org/msf/handle/10144/28678 |
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dc.identifier |
International Orthopaedics |
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dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10144/28678 |
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dc.description |
We evaluated iodine and selenium status in 575 children between 5 and 15 years with Kashin-Beck disease from endemic and non-endemic areas. Of these 267 (46%) children had goiter. The proportion of subjects with goiter was higher in the villages with Kashin-Beck disease than in the control village. In the villages with Kashin-Beck disease, 105 (23%) of the subjects had a serum thyrotropin greater than 10 mU/l as compared with 3 (4%) in the control village. The percentages of low serum thyroxine values and low serum tri-iodothyronine were greater in the villages where Kashin-Beck disease was endemic than in the control village. The percentages of low urinary iodine concentration were significantly greater in the subjects with Kashin-Beck disease. The results suggest that in areas where severe selenium deficiency is endemic, iodine deficiency is a risk factor for Kashin-Beck disease. |
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dc.language |
en |
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dc.rights |
Archived on this site with kind permission of Springer Science+Business Media |
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dc.title |
Kashin-Beck disease and iodine deficiency in Tibet. |
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