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Kashin-Beck disease and iodine deficiency in Tibet.

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dc.contributor Department of Nuclear Medicine, Hĵpital Erasme, Université Libre de Bruxelles, Brussels, Belgium. rmorenor@ulb.ac.be
dc.creator Moreno-Reyes, R
dc.creator Suetens, C
dc.creator Mathieu, F
dc.creator Begaux, F
dc.creator Zhu, D
dc.creator Rivera, M
dc.creator Boelaert, M
dc.creator Nève, J
dc.creator Perlmutter, N
dc.creator Vanderpas, J
dc.date 2001
dc.date.accessioned 2017-01-31T07:11:14Z
dc.date.available 2017-01-31T07:11:14Z
dc.identifier Kashin-Beck disease and iodine deficiency in Tibet. 2001, 25 (3):164-6notInt Orthop
dc.identifier 0341-2695
dc.identifier 11482533
dc.identifier http://hdl.handle.net/10144/28678
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/28678
dc.identifier International Orthopaedics
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/28678
dc.description We evaluated iodine and selenium status in 575 children between 5 and 15 years with Kashin-Beck disease from endemic and non-endemic areas. Of these 267 (46%) children had goiter. The proportion of subjects with goiter was higher in the villages with Kashin-Beck disease than in the control village. In the villages with Kashin-Beck disease, 105 (23%) of the subjects had a serum thyrotropin greater than 10 mU/l as compared with 3 (4%) in the control village. The percentages of low serum thyroxine values and low serum tri-iodothyronine were greater in the villages where Kashin-Beck disease was endemic than in the control village. The percentages of low urinary iodine concentration were significantly greater in the subjects with Kashin-Beck disease. The results suggest that in areas where severe selenium deficiency is endemic, iodine deficiency is a risk factor for Kashin-Beck disease.
dc.language en
dc.rights Archived on this site with kind permission of Springer Science+Business Media
dc.title Kashin-Beck disease and iodine deficiency in Tibet.


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