| dc.contributor |
Epicentre, 8 rue St Sabin, 75011 Paris, France. |
|
| dc.creator |
Borel, T |
|
| dc.creator |
Rose, A M C |
|
| dc.creator |
Guillerm, M |
|
| dc.creator |
Sidikou, F |
|
| dc.creator |
Gerstl, S |
|
| dc.creator |
Djibo, A |
|
| dc.creator |
Nathan, N |
|
| dc.creator |
Chanteau, S |
|
| dc.creator |
Guerin, P J |
|
| dc.date |
2006-10 |
|
| dc.date.accessioned |
2017-01-31T07:10:03Z |
|
| dc.date.available |
2017-01-31T07:10:03Z |
|
| dc.identifier |
High sensitivity and specificity of the Pastorex latex agglutination test for Neisseria meningitidis serogroup A during a clinical trial in Niger. 2006, 100 (10):964-9 Trans. R. Soc. Trop. Med. Hyg. |
|
| dc.identifier |
0035-9203 |
|
| dc.identifier |
16730766 |
|
| dc.identifier |
10.1016/j.trstmh.2006.03.002 |
|
| dc.identifier |
http://hdl.handle.net/10144/18359 |
|
| dc.identifier |
http://fieldresearch.msf.org/msf/handle/10144/18359 |
|
| dc.identifier |
Transactions of the Royal Society of Tropical Medicine and Hygiene |
|
| dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10144/18359 |
|
| dc.description |
There is a great need for a rapid diagnostic test to guide vaccine choice during outbreaks of meningococcal meningitis in resource-poor countries. During a randomised clinical trial conducted during an epidemic of Neisseria meningitidis serogroup A in Niger in 2003, the sensitivity and specificity of the Pastorex latex agglutination test for this serogroup under optimal field conditions were assessed, using culture and/or PCR as the gold standard. Results from 484 samples showed a sensitivity of 88% (95% CI 85-91%) and a specificity of 93% (95% CI 90-95%). Pastorex could be a good alternative to current methods, as it can be performed in a local laboratory with rapid results and is highly specific. Sensitivity can be improved with prior microscopy where feasible. A study specifically to evaluate the Pastorex test under epidemic conditions, using laboratories with limited resources, is recommended. |
|
| dc.language |
en |
|
| dc.rights |
Archived with thanks to Transactions of the Royal Society of Tropical Medicine and Hygiene |
|
| dc.title |
High sensitivity and specificity of the Pastorex latex agglutination test for Neisseria meningitidis serogroup A during a clinical trial in Niger. |
|