dc.contributor |
Médecins sans Frontières-Luxembourg, Thyolo, Malawi. |
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dc.creator |
Teck, R |
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dc.creator |
Ascurra, O |
|
dc.creator |
Gomani, P |
|
dc.creator |
Manzi, M |
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dc.creator |
Pasulani, O |
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dc.creator |
Kusamale, J |
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dc.creator |
Salaniponi, F M L |
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dc.creator |
Humblet, P |
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dc.creator |
Nunn, P |
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dc.creator |
Scano, F |
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dc.creator |
Harries, A D |
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dc.creator |
Zachariah, R |
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dc.date |
2005-03 |
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dc.date.accessioned |
2017-01-31T07:09:49Z |
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dc.date.available |
2017-01-31T07:09:49Z |
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dc.identifier |
WHO Clinical Staging of HIV Infection and Disease, Tuberculosis and Eligibility for Antiretroviral Treatment: Relationship to CD4 Lymphocyte Counts. 2005, 9 (3):258-62 Int. J. Tuberc. Lung Dis. |
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dc.identifier |
1027-3719 |
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dc.identifier |
15786887 |
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dc.identifier |
http://hdl.handle.net/10144/18292 |
|
dc.identifier |
http://fieldresearch.msf.org/msf/handle/10144/18292 |
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dc.identifier |
International Journal of Tuberculosis and Lung Disease |
|
dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10144/18292 |
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dc.description |
SETTING: Thyolo district, Malawi. OBJECTIVES: To determine in HIV-positive individuals aged over 13 years CD4 lymphocyte counts in patients classified as WHO Clinical Stage III and IV and patients with active and previous tuberculosis (TB). DESIGN: Cross-sectional study. METHODS: CD4 lymphocyte counts were determined in all consecutive HIV-positive individuals presenting to the antiretroviral clinic in WHO Stage III and IV. RESULTS: A CD4 lymphocyte count of < or = 350 cells/microl was found in 413 (90%) of 457 individuals in WHO Stage III and IV, 96% of 77 individuals with active TB, 92% of 65 individuals with a history of pulmonary TB (PTB) in the last year, 91% of 89 individuals with a previous history of PTB beyond 1 year, 81% of 32 individuals with a previous history of extra-pulmonary TB, 93% of 107 individuals with active or past TB with another HIV-related disease and 89% of 158 individuals with active or past TB without another HIV-related disease. CONCLUSIONS: In our setting, nine of 10 HIV-positive individuals presenting in WHO Stage III and IV and with active or previous TB have CD4 counts of < or = 350 cells/microl. It would thus be reasonable, in this or similar settings where CD4 counts are unavailable for clinical management, for all such patients to be considered eligible for antiretroviral therapy. |
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dc.language |
en |
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dc.publisher |
International Union Against TB and Lung Disease |
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dc.relation |
http://www.ingentaconnect.com/content/iuatld/ijtld |
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dc.rights |
Archived on this site with the kind permission of the International Union Against TB and Lung Disease, http://www.iuatld.org |
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dc.title |
WHO Clinical Staging of HIV Infection and Disease, Tuberculosis and Eligibility for Antiretroviral Treatment: Relationship to CD4 Lymphocyte Counts. |
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