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Validity, reliability and ease of use in the field of five rapid tests for the diagnosis of Plasmodium falciparum malaria in Uganda.

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dc.contributor Epicentre, 4 rue Saint Sabin, 75011 Paris, France. jguthmann@epicentre.msf.org
dc.creator Guthmann, J P
dc.creator Ruiz, A
dc.creator Priotto, G
dc.creator Kiguli, J
dc.creator Bonte, L
dc.creator Legros, D
dc.date 2008-02-14T11:38:37Z
dc.date.accessioned 2017-01-31T07:09:54Z
dc.date.available 2017-01-31T07:09:54Z
dc.identifier Validity, reliability and ease of use in the field of five rapid tests for the diagnosis of Plasmodium falciparum malaria in Uganda., 96 (3):254-7 Trans. R. Soc. Trop. Med. Hyg.
dc.identifier 0035-9203
dc.identifier 12174772
dc.identifier http://hdl.handle.net/10144/18277
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/18277
dc.identifier Transactions of the Royal Society of Tropical Medicine and Hygiene
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/18277
dc.description A study was conducted to measure the overall performance of several rapid diagnostic tests for Plasmodium falciparum infection, in order to select the most appropriate test to be used in the field. A total of 742 patients attending the out-patient department of Mbarara Hospital with a clinical suspicion of malaria were included in the study. For each patient, a thick/thin film and 5 rapid tests based on the detection of histidine-rich protein II (HRP-II) (Paracheck Pf dipstick and device, ParaHIT f, Malaria Rapid and BIO P.F.) were performed. Outcomes were validity, inter-reader reliability and 'ease of use in the field', measured by both the general characteristics of the test and by the opinion of the readers. About half (57%) of the patients were positive for P. falciparum. The Paracheck Pf (dipstick and device) was considered as the most appropriate for the use in the field, being sensitive (97%), moderately specific (88%), reliable (kappa coefficient = 0.97), easy to use and cheap (about US$ 0.5/test). The ParaHIT f represented a good alternative.
dc.language en
dc.publisher Elsevier
dc.relation http://www.sciencedirect.com/science/journal/00359203
dc.rights Archived on this site with the kind permission of Elsevier Ltd. and the Royal Society of Tropical Medicine and Hygiene, http://www.rstmh.org/transactions.asp
dc.title Validity, reliability and ease of use in the field of five rapid tests for the diagnosis of Plasmodium falciparum malaria in Uganda.


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