| dc.contributor |
Division of Infectious Disease Control, Norwegian Institute of Public Health, Oslo, Norway. philippe.guerin@epicentre.msf.org |
|
| dc.creator |
Guerin, P J |
|
| dc.creator |
Brasher, C |
|
| dc.creator |
Baron, E |
|
| dc.creator |
Mic, D |
|
| dc.creator |
Grimont, F |
|
| dc.creator |
Ryan, M |
|
| dc.creator |
Aavitsland, P |
|
| dc.creator |
Legros, D |
|
| dc.date |
2003-08-30 |
|
| dc.date.accessioned |
2017-01-31T07:09:44Z |
|
| dc.date.available |
2017-01-31T07:09:44Z |
|
| dc.identifier |
Shigella dysenteriae serotype 1 in west Africa: intervention strategy for an outbreak in Sierra Leone. 2003, 362 (9385):705-6 Lancet |
|
| dc.identifier |
1474-547X |
|
| dc.identifier |
12957094 |
|
| dc.identifier |
http://hdl.handle.net/10144/18240 |
|
| dc.identifier |
http://fieldresearch.msf.org/msf/handle/10144/18240 |
|
| dc.identifier |
Lancet |
|
| dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10144/18240 |
|
| dc.description |
In November 1999, a Médecins Sans Frontières team based in the southeastern part of Sierra Leone reported an increased number of cases of bloody diarrhoea. Shigella dysenteriae serotype 1 (Sd1) was isolated in the early cases. A total of 4218 cases of dysentery were reported in Kenema district from December, 1999, to March, 2000. The overall attack rate was 7.5%. The attack rate was higher among children younger than 5 years than in the rest of the population (11.2% vs 6.8%; relative risk=1.6; 95% CI 1.5-1.8). The case fatality was 3.1%, also higher for children younger than 5 years (6.1% vs 2.1%; relative risk=2.9; 95% CI 2.1-4.1]). Among 583 patients regarded at increased risk of death who were treated with ciprofloxacin in isolation centres, case fatality was 0.9%. A 5-day ciprofloxacin regimen, targeted to the most severe cases of bloody diarrhoea, was highly effective. This is the first time a large outbreak caused by Sd1 has been reported in west Africa. |
|
| dc.language |
en |
|
| dc.publisher |
Elsevier |
|
| dc.relation |
http://www.thelancet.com |
|
| dc.rights |
Reproduced on this site with permission of Elsevier Ltd. Please see www.thelancet.com for further relevant comment. |
|
| dc.title |
Shigella dysenteriae serotype 1 in west Africa: intervention strategy for an outbreak in Sierra Leone. |
|