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Multidrug-Resistant Tuberculosis in Central Asia.

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dc.contributor Médecins Sans Frontières Aral Sea Area Programme, Uzbekistan and Turkmenistan, Tashkent, Uzbekistan. hom@msfh-tashkent.uz
dc.creator Cox, H
dc.creator Orozco, J D
dc.creator Male, R
dc.creator Ruesch-Gerdes, S
dc.creator Falzon, D
dc.creator Small, I
dc.creator Doshetov, D
dc.creator Kebede, Y
dc.creator Aziz, M
dc.date 2004-05
dc.date.accessioned 2017-01-31T07:09:35Z
dc.date.available 2017-01-31T07:09:35Z
dc.identifier Multidrug-Resistant Tuberculosis in Central Asia. 2004, 10 (5):865-72 Emerging Infect. Dis.
dc.identifier 1080-6040
dc.identifier 15200821
dc.identifier http://hdl.handle.net/10144/17739
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/17739
dc.identifier Emerging Infectious Diseases
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/17739
dc.description Multidrug-resistant tuberculosis (MDR-TB) has emerged as a major threat to TB control, particularly in the former Soviet Union. To determine levels of drug resistance within a directly observed treatment strategy (DOTS) program supported by Médecins Sans Frontières in two regions in Uzbekistan and Turkmenistan, Central Asia, we conducted a cross-sectional survey of smear-positive TB patients in selected districts of Karakalpakstan (Uzbekistan) and Dashoguz (Turkmenistan). High levels of MDR-TB were found in both regions. In Karakalpakstan, 14 (13%) of 106 new patients were infected with MDR-TB; 43 (40%) of 107 previously treated patients were similarly infected. The proportions for Dashoguz were 4% (4/105 patients) and 18% (18/98 patients), respectively. Overall, 27% of patients with positive smear results whose infections were treated through the DOTS program in Karakalpakstan and 11% of similar patients in Dashoguz were infected with multidrug-resistant strains of TB on admission. These results show the need for concerted action by the international community to contain transmission and reduce the effects of MDR-TB.
dc.language en
dc.relation http://www.cdc.gov/ncidod/eid
dc.rights Archived on this site by permission of CDC
dc.title Multidrug-Resistant Tuberculosis in Central Asia.

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