| dc.contributor |
Médecins sans Frontières, Dupréstraat 94, B-1090 Brussels, Belgium. |
|
| dc.creator |
Marlet, M V L |
|
| dc.creator |
Wuillaume, F |
|
| dc.creator |
Jacquet, D |
|
| dc.creator |
Quispe, K W |
|
| dc.creator |
Dujardin, J C |
|
| dc.creator |
Boelaert, M |
|
| dc.date |
2008-02-07T16:21:25Z |
|
| dc.date.accessioned |
2017-01-31T07:09:34Z |
|
| dc.date.available |
2017-01-31T07:09:34Z |
|
| dc.identifier |
A neglected disease of humans: a new focus of visceral leishmaniasis in Bakool, Somalia., 97 (6):667-71 Trans. R. Soc. Trop. Med. Hyg. |
|
| dc.identifier |
0035-9203 |
|
| dc.identifier |
16117959 |
|
| dc.identifier |
http://hdl.handle.net/10144/17719 |
|
| dc.identifier |
http://fieldresearch.msf.org/msf/handle/10144/17719 |
|
| dc.identifier |
Transactions of the Royal Society of Tropical Medicine and Hygiene |
|
| dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10144/17719 |
|
| dc.description |
Visceral leishmaniasis (VL) was observed in children in Bakool region, Somalia, an area where VL has not been reported before. We describe the extent of the problem in this war- and famine-stricken area. A retrospective analysis was done of all cases admitted to a VL treatment centre between July 2000 and August 2001. Patients with longstanding fever, splenomegaly and a positive direct agglutination test (DAT; titre > 1:3200) were treated as suspected VL cases. A rapid epidemiological and entomological assessment was performed in the area. Species identification was attempted from blood samples by polymerase chain reaction-restriction fragment length polymorphism analysis of cysteine proteinase B genes. In 1 year, 230 serologically-positive cases were diagnosed as VL, and response to therapy was good in 91.6% of the 225 treated with sodium stibogluconate. Parasitological confirmation was attempted and obtained in 2 cases. Parasites were found to be most similar to Sudanese and Ethiopian reference strains of the Leishmania donovani complex. In a serological survey of 161 healthy displaced persons, 15% were positive by the leishmanin skin test and 3 (2%) were positive by the DAT. The sandfly captures showed Phlebotomus martini and P. vansomerenae. VL seems to be a longstanding and serious health problem in Bakool region. Food insecurity might have contributed to the emergence and detection of VL in this area. |
|
| dc.language |
en |
|
| dc.publisher |
Elsevier |
|
| dc.relation |
http://www.sciencedirect.com/science/journal/00359203 |
|
| dc.rights |
Archived on this site with the kind permission of Elsevier Ltd. and the Royal Society of Tropical Medicine and Hygiene, http://www.rstmh.org/transactions.asp |
|
| dc.title |
A neglected disease of humans: a new focus of visceral leishmaniasis in Bakool, Somalia. |
|