| dc.contributor |
Médecins Sans Frontières-Luxembourg, Thyolo District, Malawi. zachariah@internet.lu |
|
| dc.creator |
Zachariah, R |
|
| dc.creator |
Spielmann M P |
|
| dc.creator |
Harries, A D |
|
| dc.creator |
Salaniponi, F M L |
|
| dc.date |
2008-02-07T16:19:23Z |
|
| dc.date.accessioned |
2017-01-31T07:09:34Z |
|
| dc.date.available |
2017-01-31T07:09:34Z |
|
| dc.identifier |
Moderate to severe malnutrition in patients with tuberculosis is a risk factor associated with early death., 96 (3):291-4 Trans. R. Soc. Trop. Med. Hyg. |
|
| dc.identifier |
0035-9203 |
|
| dc.identifier |
12174782 |
|
| dc.identifier |
http://hdl.handle.net/10144/17718 |
|
| dc.identifier |
http://fieldresearch.msf.org/msf/handle/10144/17718 |
|
| dc.identifier |
Transactions of the Royal Society of Tropical Medicine and Hygiene |
|
| dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10144/17718 |
|
| dc.description |
A study was conducted in new patients registered with tuberculosis (TB) in a rural district of Malawi to determine (i) the prevalence of malnutrition on admission and (ii) the association between malnutrition and early mortality (defined as death within the first 4 weeks of treatment). There were 1181 patients with TB (576 men and 605 women), whose overall rate of infection with human immunodeficiency virus (HIV) was 80%. 673 TB patients (57%) were malnourished on admission (body mass index [BMI] < 18.5 kg/m2). There were 259 patients (22%) with mild malnutrition (BMI 17.0-18.4 kg/m2), 168 (14%) with moderate malnutrition (BMI 16.0-16.9 kg/m2) and 246 (21%) with severe malnutrition (BMI < 15.9 kg/m2). 95 patients (8%) died during the first 4 weeks. Significant risk factors for early mortality included increasing degrees of malnutrition, age > 35 years, and HIV seropositivity. Among all the 1181 patients, 10.9% of the 414 patients with moderate to severe malnutrition died in the first 4 weeks compared with 6.5% of the 767 patients with normal to mild malnutrition (odds ratio 1.8, 95% confidence interval 1.1-2.7). In patients with TB, BMI < 17.0 kg/m2 is associated with an increased risk of early death. |
|
| dc.language |
en |
|
| dc.publisher |
Elsevier |
|
| dc.relation |
http://www.sciencedirect.com/science/journal/00359203 |
|
| dc.rights |
Archived on this site with the kind permission of Elsevier Ltd. and the Royal Society of Tropical Medicine and Hygiene, http://www.rstmh.org/transactions.asp |
|
| dc.title |
Moderate to severe malnutrition in patients with tuberculosis is a risk factor associated with early death. |
|