| dc.contributor |
Médecins sans Frontières-Holland, Amsterdam, The Netherlands. koert.ritmeijer@amsterdam.msf.org |
|
| dc.creator |
Ritmeijer, K |
|
| dc.creator |
Melaku, Y |
|
| dc.creator |
Mueller, M |
|
| dc.creator |
Kipngetich, S |
|
| dc.creator |
O'keeffe, C |
|
| dc.creator |
Davidson, R N |
|
| dc.date |
2006-01 |
|
| dc.date.accessioned |
2017-01-31T07:09:20Z |
|
| dc.date.available |
2017-01-31T07:09:20Z |
|
| dc.identifier |
Evaluation of a New Recombinant K39 Rapid Diagnostic Test for Sudanese Visceral Leishmaniasis. 2006, 74 (1):76-80 Am. J. Trop. Med. Hyg. |
|
| dc.identifier |
0002-9637 |
|
| dc.identifier |
16407349 |
|
| dc.identifier |
http://hdl.handle.net/10144/17289 |
|
| dc.identifier |
http://fieldresearch.msf.org/msf/handle/10144/17289 |
|
| dc.identifier |
The American Journal of Tropical Medicine and Hygiene |
|
| dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10144/17289 |
|
| dc.description |
A new rK39 rapid diagnostic dipstick test (DiaMed-IT-Leish) was compared with aspiration and a direct agglutination test (DAT) for diagnosis of visceral leishmaniasis (VL) in 201 parasitologically confirmed cases, 133 endemic controls, and in 356 clinical suspects in disease-endemic and -epidemic areas in Sudan. The sensitivity of the rK39 test in parasitologically confirmed VL cases was 90%, whereas the specificity in disease-endemic controls was 99%. The sensitivity of the DAT was 98%. In clinically suspected cases, the sensitivity of the rK39 test was 81% and the specificity was 97%. When compared with the diagnostic protocol based on the DAT and aspiration used by Médecins sans Frontières in epidemic situations, the positive predictive value was 98%, and the negative predictive value was 71%. This rK39 rapid diagnostic test is suitable for screening as well as diagnosis of VL. Further diagnostic work-up of dipstick-negative patients with clinically suspected VL is important. The ease and convenience of the dipstick test will allow decentralization and improved access to care in disease-endemic areas in Sudan. |
|
| dc.language |
en |
|
| dc.publisher |
Published by: American Society of Tropical Medicine and Hygiene |
|
| dc.relation |
http://www.ajtmh.org |
|
| dc.rights |
Archived on this site with the kind permission of the American Society of Tropical Medicine and Hygiene, www.astmh.org |
|
| dc.title |
Evaluation of a New Recombinant K39 Rapid Diagnostic Test for Sudanese Visceral Leishmaniasis. |
|