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Cotrimoxazole prophylaxis for HIV-positive TB patients in developing countries.

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dc.contributor Medecins sans Frontieres, Operational Research HIV-TB, Medical department, Brussels Operational Center, 68 Rue de Gaspench, L-1617 Luxemburg. zachariah@internet.lu
dc.creator Zachariah, R
dc.creator Massaquoi, M
dc.date 2006-04
dc.date.accessioned 2017-01-31T07:09:19Z
dc.date.available 2017-01-31T07:09:19Z
dc.identifier Cotrimoxazole prophylaxis for HIV-positive TB patients in developing countries. 2006, 36 (2):79-82notTrop Doct
dc.identifier 0049-4755
dc.identifier 16611438
dc.identifier 10.1258/004947506776593314
dc.identifier http://hdl.handle.net/10144/17283
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/17283
dc.identifier Tropical Doctor
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/17283
dc.description Despite provisional recommendations from the World Health Organization and UNAIDS that cotrimoxazole (CTX) prophylaxis be offered to all individuals living with AIDS, including HIV-positive patients with TB, its routine use in developing countries particularly Africa has been minimal. Concerns were expressed regarding its effectiveness in areas of high bacterial resistance, that its widespread use might substantially increase bacterial cross-resistance in the community and that this intervention might promote resistance of malaria parasites to sulphadoxine-pyrimethamine. We review the current evidence on the above concerns and highlight the main operational considerations related to implementing CTX prophylaxis as a basic component of care for HIV-positive TB patients in developing countries.
dc.language en
dc.relation http://td.rsmjournals.com
dc.rights Reproduced on this site with the permission of Royal Society of Medicine Press, London (www.rsmpress.co.uk/td.htm)
dc.title Cotrimoxazole prophylaxis for HIV-positive TB patients in developing countries.


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