dc.contributor |
Epicentre, 8 rue Saint Sabin, 75011 Paris, France. jguthmann@epicentre.msf.org |
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dc.creator |
Guthmann, J P |
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dc.creator |
Kasparian, S |
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dc.creator |
Phetsouvanh, R |
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dc.creator |
Nathan, N |
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dc.creator |
Garcia, M |
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dc.creator |
Phompida, S |
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dc.creator |
Brockman, A |
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dc.creator |
Gastellu-Etchegorry, M |
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dc.creator |
Legros, D |
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dc.date |
2002-09 |
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dc.date.accessioned |
2017-01-31T07:09:11Z |
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dc.date.available |
2017-01-31T07:09:11Z |
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dc.identifier |
The Efficacy of Chloroquine for the Treatment of Acute, Uncomplicated, Plasmodium Falciparum Malaria in Laos. 2002, 96 (6):553-7 Ann. Trop. Med. Parasitol. |
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dc.identifier |
0003-4983 |
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dc.identifier |
12396318 |
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dc.identifier |
10.1179/000349802125001654 |
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dc.identifier |
http://hdl.handle.net/10144/17278 |
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dc.identifier |
http://fieldresearch.msf.org/msf/handle/10144/17278 |
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dc.identifier |
Annals of Tropical Medicine and Parasitology |
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dc.identifier.uri |
http://dspace.mediu.edu.my:8181/xmlui/handle/10144/17278 |
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dc.description |
To assess the local efficacy of chloroquine for the treatment of acute, uncomplicated, Plasmodium falciparum malaria, children and adults from Sekong province (an area of Laos with a low intensity of transmission) were tested in a 28-day, in-vivo study. Complete data were collected from 88 of the 102 subjects enrolled between October 1999 and September 2000. After genotypic analysis to distinguish recrudescing infections from re-infections, 35 (39.7%, with a 95% confidence interval of 29.5%-50.7%) of these 88 patients were considered treatment failures. These results seriously question the use of chloroquine as the first-line treatment for P. falciparum malaria in the study area. |
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dc.language |
en |
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dc.publisher |
Published by: Maney Publishing |
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dc.relation |
http://www.maney.co.uk/journals/atmp |
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dc.rights |
Archived on this site with the kind permission of Maney Publishing |
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dc.title |
The Efficacy of Chloroquine for the Treatment of Acute, Uncomplicated, Plasmodium Falciparum Malaria in Laos. |
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