المستودع الأكاديمي جامعة المدينة

Evaluation of Three Rapid Tests for Diagnosis of P. Falciparum and P. Vivax Malaria in Colombia.

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dc.contributor Médecins sans Frontières (MSF), London, UK. ingrid_vandenbroek@yahoo.com
dc.creator van den Broek, I
dc.creator Hill, O
dc.creator Gordillo, F
dc.creator Angarita, B
dc.creator Hamade, P
dc.creator Counihan, H
dc.creator Guthmann, J P
dc.date 2006-12
dc.date.accessioned 2017-01-31T07:09:20Z
dc.date.available 2017-01-31T07:09:20Z
dc.identifier Evaluation of Three Rapid Tests for Diagnosis of P. Falciparum and P. Vivax Malaria in Colombia. 2006, 75 (6):1209-15 Am. J. Trop. Med. Hyg.
dc.identifier 0002-9637
dc.identifier 17172395
dc.identifier http://hdl.handle.net/10144/17270
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/17270
dc.identifier The American Journal of Tropical Medicine and Hygiene
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/17270
dc.description The diagnostic capacity of three malaria rapid diagnostic tests (RDTs), NOW-Malaria-ICT, OptiMAL-IT, and Paracheck-Pf, was evaluated against expert microscopy in Colombia. We tested 896 patients, of whom microscopy confirmed 139 P. falciparum, 279 P. vivax, and 13 mixed P.f/P.v infections and 465 negatives. Paracheck-Pf and NOW-malaria-ICT were more accurate in detecting P. falciparum (sensitivities 90.8% and 90.1%, respectively) in comparison with Optimal-IT (83.6%). NOW showed an acceptable Pf detection rate at low densities (< 500/microL), but resulted in a higher proportion of false positives. For P. vivax diagnosis, Optimal-IT had a higher sensitivity than NOW (91.0% and 81.4%, respectively). The choice between the two Pf/Pv detecting RDTs balances P. falciparum and P. vivax detection rates. Considering some degree of P. falciparum overtreatment and failure to detect all P. vivax cases as more acceptable than missing some cases of P. falciparum, we recommend careful implementation of NOW-malaria-ICT in areas where microscopy is lacking. The price is however still a constraint.
dc.language en
dc.relation http://www.ajtmh.org
dc.relation http://www.ajtmh.org
dc.relation http://www.ajtmh.org
dc.rights Archived on this site with the kind permission of the American Society of Tropical Medicine and Hygiene,www.astmh.org
dc.title Evaluation of Three Rapid Tests for Diagnosis of P. Falciparum and P. Vivax Malaria in Colombia.


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