المستودع الأكاديمي جامعة المدينة

Estimating transmission intensity for a measles epidemic in Niamey, Niger: lessons for intervention.

أعرض تسجيلة المادة بشكل مبسط

dc.contributor Epicentre, 8 rue Saint Sabin, 75011 Paris, France. rebecca.grais@epicentre.msf.org
dc.creator Grais, R
dc.creator Ferrari, M J
dc.creator Dubray, C
dc.creator Bjørnstad, O N
dc.creator Grenfell, B T
dc.creator Djibo, A
dc.creator Fermon, F
dc.creator Guerin, P J
dc.date 2006-09
dc.date.accessioned 2017-01-31T07:09:19Z
dc.date.available 2017-01-31T07:09:19Z
dc.identifier Estimating transmission intensity for a measles epidemic in Niamey, Niger: lessons for intervention. 2006, 100 (9):867-73 Trans. R. Soc. Trop. Med. Hyg.
dc.identifier 0035-9203
dc.identifier 16540134
dc.identifier 10.1016/j.trstmh.2005.10.014
dc.identifier http://hdl.handle.net/10144/17268
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/17268
dc.identifier Transactions of the Royal Society of Tropical Medicine and Hygiene
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/17268
dc.description The objective of this study is to estimate the effective reproductive ratio for the 2003-2004 measles epidemic in Niamey, Niger. Using the results of a retrospective and prospective study of reported cases within Niamey during the 2003-2004 epidemic, we estimate the basic reproductive ratio, effective reproductive ratio (RE) and minimal vaccination coverage necessary to avert future epidemics using a recent method allowing for estimation based on the epidemic case series. We provide these estimates for geographic areas within Niamey, thereby identifying neighbourhoods at high risk. The estimated citywide RE was 2.8, considerably lower than previous estimates, which may help explain the long duration of the epidemic. Transmission intensity varied during the course of the epidemic and within different neighbourhoods (RE range: 1.4-4.7). Our results indicate that vaccination coverage in currently susceptible children should be increased by at least 67% (vaccine efficacy 90%) to produce a citywide vaccine coverage of 90%. This research highlights the importance of local differences in vaccination coverage on the potential impact of epidemic control measures. The spatial-temporal spread of the epidemic from district to district in Niamey over 30 weeks suggests that targeted interventions within the city could have an impact.
dc.language en
dc.publisher Elsevier
dc.relation http://www.sciencedirect.com/science/journal/00359203
dc.rights Archived on this site with the kind permission of Elsevier Ltd. and the Royal Society of Tropical Medicine and Hygiene, http://www.rstmh.org/transactions.asp
dc.title Estimating transmission intensity for a measles epidemic in Niamey, Niger: lessons for intervention.


الملفات في هذه المادة

الملفات الحجم الصيغة عرض

لا توجد أي ملفات مرتبطة بهذه المادة.

هذه المادة تبدو في المجموعات التالية:

أعرض تسجيلة المادة بشكل مبسط