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Clonal reconquest of antibiotic-susceptible Salmonella enterica serotype Typhi in Son La Province, Vietnam.

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dc.contributor Centre National de Référence des Salmonella, Centre Collaborateur OMS de Référence et de Recherche pour les Salmonella, Unité de Biodiversité des Bactéries Pathogènes Emergentes, INSERM U389, Institut Pasteur, Paris, France. fxweill@pasteur.fr
dc.creator Weill, F X
dc.creator Tran, H H
dc.creator Roumagnac, P
dc.creator Fabre, L
dc.creator Minh, N B
dc.creator Stavnes, T L
dc.creator Lassen, J
dc.creator Bjune, G
dc.creator Grimont, P A D
dc.creator Guerin, P J
dc.date 2007-06
dc.date.accessioned 2017-01-31T07:09:14Z
dc.date.available 2017-01-31T07:09:14Z
dc.identifier Clonal reconquest of antibiotic-susceptible Salmonella enterica serotype Typhi in Son La Province, Vietnam. 2007, 76 (6):1174-81 Am. J. Trop. Med. Hyg.
dc.identifier 0002-9637
dc.identifier 17556632
dc.identifier http://hdl.handle.net/10144/17240
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/17240
dc.identifier American Journal of Tropical Medicine and Hygiene
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/17240
dc.description In the last three decades, high rates of resistance to common first-line antimicrobial agents have been reported in Salmonella enterica serotype Typhi (Typhi), the causative organism of typhoid fever (TF), in many regions of the world, especially in South East Asia. Analysis of Typhi strains isolated from outbreaks and sporadic cases of TF in Son La province, northwest Vietnam, in 2002 revealed that 94.5% (85/90) of the isolates were fully susceptible to amoxicillin, chloramphenicol, cotrimoxazole, tetracycline, and nalidixic acid. There was a clear decline in the occurrence of multi-drug resistant (MDR) Typhi isolates collected in this province in 2002 (4.4%) compared with the period 1995-1999 in the same province (30.8-100%). By using molecular (IS200 profiling, PstI-ribotyping, XbaI-pulsed-field gel electrophoresis, and haplotyping) and phage-typing methods, we showed that the Typhi isolates from Son La province in 2002 were genetically related; however, they were unrelated to the previous MDR clones established in Vietnam.
dc.language en
dc.rights Archived on this site with the kind permission of the American Society of Tropical Medicine and Hygiene, www.astmh.org
dc.title Clonal reconquest of antibiotic-susceptible Salmonella enterica serotype Typhi in Son La Province, Vietnam.


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