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Evaluation of a 5-year programme to prevent mother-to-child transmission of HIV infection in Northern Uganda

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dc.contributor Epicentre, Paris, France; Medecins Sans Frontieres, Kampala, Uganda; Arua Regional District Hospital, Ministry of Health, Arua, Uganda; Medecins Sans Frontieres, Paris, France
dc.creator Ahoua, Laurence
dc.creator Ayikoru, Harriet
dc.creator Gnauck, Katherine
dc.creator Odaru, Grace
dc.creator Odar, Emmanuel
dc.creator Ondoa-Onama, Christine
dc.creator Pinoges, Loretxu
dc.creator Balkan, Suna
dc.creator Olson, David
dc.creator Pujades-Rodríguez, Mar
dc.date 2010-07-13
dc.date.accessioned 2017-01-31T07:25:54Z
dc.date.available 2017-01-31T07:25:54Z
dc.identifier J. Trop. Pediatr. 2010;56(1):43-52
dc.identifier 1465-3664
dc.identifier 19602489
dc.identifier 10.1093/tropej/fmp054
dc.identifier http://hdl.handle.net/10144/120332
dc.identifier http://fieldresearch.msf.org/msf/handle/10144/120332
dc.identifier Journal of tropical pediatrics
dc.identifier.uri http://dspace.mediu.edu.my:8181/xmlui/handle/10144/120332
dc.description Prevention of mother-to-child transmission (PMTCT) is essential in HIV/AIDS control. We analysed 2000-05 data from mother-infant pairs in our PMTCT programme in rural Uganda, examining programme utilization and outcomes, HIV transmission rates and predictors of death or loss to follow-up (LFU). Out of 19,017 women, 1,037 (5.5%) attending antenatal care services tested HIV positive. Of these, 517 (50%) enrolled in the PMTCT programme and gave birth to 567 infants. Before tracing, 303 (53%) mother-infant pairs were LFU. Reasons for dropout were infant death and lack of understanding of importance of follow-up. Risk of death or LFU was higher among infants with no or incomplete intrapartum prophylaxis (OR = 1.90, 95% CI 1.07-3.36) and of weaning age <6 months (OR 2.55, 95% CI 1.42-4.58), and lower in infants with diagnosed acute illness (OR 0.30, 95% CI 0.16-0.55). Mother-to-child HIV cumulative transmission rate was 8.3%, and 15.5% when HIV-related deaths were considered. Improved tracking of HIV-exposed infants is needed in PMTCT programmes where access to early infant diagnosis is still limited.
dc.language en
dc.relation http://www.ncbi.nlm.nih.gov/pubmed
dc.rights Published by Oxford University Press Archived on this site with kind permission from Oxford University Press
dc.title Evaluation of a 5-year programme to prevent mother-to-child transmission of HIV infection in Northern Uganda
dc.type Article


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