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http://dspace.mediu.edu.my:8181/xmlui/handle/1721.1/3936| Title: | Nanoparticles for Targeted Drug Delivery |
| Keywords: | nanoparticles targeted drug delivery near infrared sensitive Au-Au<sub>2</sub>S nanoparticles anti-cancer drugs NIR irradiation adsorption of cis-platin |
| Issue Date: | 9-Oct-2013 |
| Description: | Nanoparticles were synthesized and modified for target drug delivery. The research involved the aqueous synthesis of near infrared (NIR) sensitive Au-Au<sub>2</sub>S nanoparticles. An anti-cancer drug (<i>cis-platin</i>) was subsequently adsorbed onto the Au-Au<sub>2</sub>S nanoparticle surface via the 11-mercaptoundecanoic acid layers. The results showed that the degree of adsorption of cis-platin onto Au-Au<sub>2</sub>S nanoparticles was controlled by the pH value of solution, and the rate of drug release was sensitive to NIR irradiation. The results of the synthesis, drug-release properties and nanoparticle-cell interactions will be discussed. Singapore-MIT Alliance (SMA) |
| URI: | http://koha.mediu.edu.my:8181/xmlui/handle/1721 |
| Other Identifiers: | http://hdl.handle.net/1721.1/3936 |
| Appears in Collections: | MIT Items |
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