Nanoparticles for Targeted Drug Delivery

Please use this identifier to cite or link to this item: http://dspace.mediu.edu.my:8181/xmlui/handle/1721.1/3936

Full metadata record

DC Field	Value	Language
dc.creator	Chow, Gan-Moog	-
dc.date	2003-12-16T14:00:17Z	-
dc.date	2003-12-16T14:00:17Z	-
dc.date	2004-01	-
dc.date.accessioned	2013-10-09T02:33:15Z	-
dc.date.available	2013-10-09T02:33:15Z	-
dc.date.issued	2013-10-09	-
dc.identifier	http://hdl.handle.net/1721.1/3936	-
dc.identifier.uri	http://koha.mediu.edu.my:8181/xmlui/handle/1721	-
dc.description	Nanoparticles were synthesized and modified for target drug delivery. The research involved the aqueous synthesis of near infrared (NIR) sensitive Au-Au<sub>2</sub>S nanoparticles. An anti-cancer drug (<i>cis-platin</i>) was subsequently adsorbed onto the Au-Au<sub>2</sub>S nanoparticle surface via the 11-mercaptoundecanoic acid layers. The results showed that the degree of adsorption of cis-platin onto Au-Au<sub>2</sub>S nanoparticles was controlled by the pH value of solution, and the rate of drug release was sensitive to NIR irradiation. The results of the synthesis, drug-release properties and nanoparticle-cell interactions will be discussed.	-
dc.description	Singapore-MIT Alliance (SMA)	-
dc.format	12186 bytes	-
dc.format	application/pdf	-
dc.language	en_US	-
dc.relation	Molecular Engineering of Biological and Chemical Systems (MEBCS);	-
dc.subject	nanoparticles	-
dc.subject	targeted drug delivery	-
dc.subject	near infrared sensitive Au-Au<sub>2</sub>S nanoparticles	-
dc.subject	anti-cancer drugs	-
dc.subject	NIR irradiation	-
dc.subject	adsorption of cis-platin	-
dc.title	Nanoparticles for Targeted Drug Delivery	-
dc.type	Article	-
Appears in Collections:	MIT Items

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